… the membrane structure, giving a … contributed toward the stronger double-helix DNA-binding
affinity in BF2-C. We have summarized a list of AMPs with reported intracellular targeting …

… contributed by polar amino acid residues such as arginine, lysine and histidine 26. Antimicrobial
… -sheet, loop and extended structure, however, α-helices and β-sheet structure are more …

… Whether on one side, microorganisms evolved strategies to … and act intracellularly,
consequently contributing to increasing … sets, strategies of structural design and peptide …

… Mechanism of intracellular targeting … Length also affects the secondary structure and action
mode of the peptide… residues, some of which may not contribute to antibacterial activity [78,79]…

… structures. The main mechanisms of AMPs were divided into membrane targets and intracellular
targets… For most AMPs, the high affinity for microbial membranes contribute to the overall …

… , antimicrobial peptides (AMPs) and cell-penetrating peptides (CPPs) have shown great
potential to treat such infections by acting directly on the intracellular … existing peptide structures …

… ], contributing an important role in autoimmune diseases [20]. … antimicrobial activity are
very effective against intracellular … database of antimicrobial activity and structure of peptides (…

… -membrane interactions and investigate the effect of peptides on the structure of lipid bilayers.
… Liposomes are unilamellar or multilamellar structures obtained by suspending lipids in an …

… perspective on indolicidin’s structure by the formation of extended and β-turn structures [27]. …
are intrinsically related to the presence of PXP motifs, which contribute to the ordered …

… Gramicidin was the first reported antimicrobial peptide (AMP), isolated from the soil bacteria
… global interest and research efforts were devoted to antimicrobial peptides, due to the rise of …