The role and activity of SWI/SNF chromatin remodelers

T Bieluszewski, S Prakash, T Roulé… - Annual Review of Plant …, 2023 - annualreviews.org
… with the SANT domains of SWI3 homologs, anchor the ATPase … findings indicate that SWI/SNF
CRCs are required for both … remodeling and enhancer accessibility rely on SWI/SNF CRC …

Architecture of SWI/SNF chromatin remodeling complex

Z Zhang, X Wang, J Xin, Z Ding, S Liu, Q Fang… - Protein & …, 2018 - academic.oup.com
… The two lobes of the ATPase domain are anchored to the two … that the ATPase domain is
not required for stable nucleosome … SWI/SNF nucleosome binding states in which the histone

Mechanism of action of the SWI/SNF family complexes

K Chen, J Yuan, Y Sia, Z Chen - Nucleus, 2023 - Taylor & Francis
… around the arginine anchor region of the SnAc domain. (d) … the nucleosome remodeling
activity of SWI/SNF and RSC in … required diversity and sensitivity in response to the histone

SWI/SNF chromatin remodelers: structural, functional and mechanistic implications

A Singh, SB Modak, MM Chaturvedi… - Cell Biochemistry and …, 2023 - Springer
… , recombination and repair etc. require the transition of the … partially purified SWI/SNF-like
remodeling complex (SLC) … Snf5/Swi3/Snf2 HSA and anchor domain interactions), but also …

[图书][B] An insight into different modes of remodeler regulation: Focus on Saccharomyces cerevisiae SWI/SNF

S Kundu - 2016 - search.proquest.com
… the context of SWI/SNF remodeling due to its requirement for … , SnAC and AT hook motifs
with respect to SWI/SNF activity. … ) and acts as a histone anchor domain, while the AT hooks …

Structure of chromatin remodeler Swi2/Snf2 in the resting state

X Xia, X Liu, T Li, X Fang, Z Chen - Nature Structural & Molecular …, 2016 - nature.com
… In cells, SWI/SNF and RSC control the expression of … remodeling, probably the required
conformational changes of the enzyme that couples ATP hydrolysis and alters the DNA-histone

Regulation of ATP-dependent chromatin remodelers: accelerators/brakes, anchors and sensors

S Paul, B Bartholomew - Biochemical Society Transactions, 2018 - portlandpress.com
… of this type of anchor is the SnAC domain in SWI/SNF complexes which required the correct
… In these conditions, SWI/SNF lacking the SnAC domain was found to remodel nucleosomes …

[HTML][HTML] Loss of Snf5 induces formation of an aberrant SWI/SNF complex

P Sen, J Luo, A Hada, SG Hailu, ML Dechassa… - Cell Reports, 2017 - cell.com
… and nucleosome remodeling activities of SWI/SNF. Snf5 is also required for SWI/SNF … each
of the five histone positions and for wild-type and Δsnf5 SWI/SNF. Signals were normalized …

The AT-hook is an evolutionarily conserved auto-regulatory domain of SWI/SNF required for cell lineage priming

D Saha, S Hailu, A Hada, J Lee, J Luo… - Nature …, 2023 - nature.com
… modifiers and generally thought to help anchor them to DNA. We … the nucleosome remodeling
activity of WT and ΔAT SWI/SNF … laevis histones. In order to examine a single round of …

The mechanisms of action of chromatin remodelers and implications in development and disease

RK Sahu, S Singh, RS Tomar - Biochemical Pharmacology, 2020 - Elsevier
… site and histone-specific, but they lack DNA binding domain; hence they require additional
… Mutations in SWI/SNF complex is more prominent than other remodelling complexes, and it …