The landscape of accessible chromatin in mammalian preimplantation embryos

J Wu, BO Huang, HE Chen, Q Yin, Y Liu, Y Xiang… - Nature, 2016 - nature.com
chromatin landscape and its dynamics in this period remain unexplored. Here we report a
genome-wide map of accessible chromatin in … for transposase-accessible chromatin with high …

Genomic landscape of CpG rich elements in human

VN Babenko, IV Chadaeva, YL Orlov - BMC evolutionary biology, 2017 - Springer
… We used human genome version hg19; mouse genome version mm10; dog … 100–200 bp)
DNA fragments. They indicate open or accessible chromatin where DNA is not tightly wrapped …

An atlas of chromatin accessibility in the adult human brain

JF Fullard, ME Hauberg, J Bendl, G Egervari… - Genome …, 2018 - genome.cshlp.org
… Furthermore, differentially accessible chromatin overlaps with the genetic architecture of …
this human brain chromatin accessibility atlas as an online database “Brain Open Chromatin

Replication landscape of the human genome

N Petryk, M Kahli, Y d'Aubenton-Carafa… - Nature …, 2016 - nature.com
… We, therefore, suggest that the human genome undergoes a superposition of efficient
initiation at circumscribed ‘master’ zones identified here and more dispersed, less efficient …

Analysis of accessible chromatin landscape in the inner cell mass and trophectoderm of human blastocysts

M Yang, X Tao, S Titus, T Zhao… - Molecular Human …, 2020 - academic.oup.com
… This is the first study to compare the landscape of the accessible chromatin between ICM
and TE of human preimplantation embryos, which unveiled chromatin-level epigenetic …

A cell atlas of chromatin accessibility across 25 adult human tissues

K Zhang, JD Hocker, M Miller, X Hou, J Chiou… - BioRxiv, 2021 - biorxiv.org
… To profile the activity of human gene regulatory elements in diverse cell types and tissues
in the human body, we applied single cell chromatin accessibility assays to 25 distinct human

Chromatin accessibility landscape of cutaneous T cell lymphoma and dynamic response to HDAC inhibitors

K Qu, LC Zaba, AT Satpathy, PG Giresi, R Li, Y Jin… - Cancer cell, 2017 - cell.com
… However, the landscape of the CTCL epigenome … accessible chromatin landscapes in
clinical CTCL samples and their dynamic response to HDACi. The pattern of accessible chromatin

Characterizing the nuclease accessibility of DNA in human cells to map higher order structures of chromatin

U Schwartz, A Németh, S Diermeier… - Nucleic acids …, 2019 - academic.oup.com
… The sequenced paired-end reads were mapped to the UCSC human genome version 37
(hg19) using the local alignment option of bowtie2 with following parameters—very-sensitve-…

Chromatin accessibility: methods, mechanisms, and biological insights

AR Mansisidor, VI Risca - Nucleus, 2022 - Taylor & Francis
… Here, we review the ongoing development of accessibility … the accessibility landscape,
and we detail the many important biological functions that are linked to chromatin accessibility. …

A comparative atlas of single-cell chromatin accessibility in the human brain

YE Li, S Preissl, M Miller, ND Johnson, Z Wang, H Jiao… - Science, 2023 - science.org
… -accessible chromatin using sequencing (snATAC-seq), we explored open chromatin landscapes
… candidate cis-regulatory DNA elements (cCREs) in the human genome. Nearly a third …