… Non-coding regions comprise most of the human genome and harbor a significant fraction …
in human cortical neurogenesis by contrasting chromatin accessibility and gene expression in …

… To study the impact of genetic variation on the chromatin landscape, we used allele-specific
measurement of open chromatin to identify genotype-dependent sites (ASCs). While the …

… Figure 2 (preceding page): The single-stranded accessible chromatin landscape is distinct
from total open chromatin genomic maps. (a) DESeq2 analysis of GM12878 ATAC and KAS-…

… mapping of the accessible chromatin landscape of individual … the methylome landscape and
different chromatin features have … in the mouse or human genome as regions spanning 1 kb …

… gene regulatory elements to drive transcription on a genome-… Most gene regulatory activity
occurs within accessible chromatin, … retain chromatin accessible peaks in the human genome …

… of chromatin organization in human tissues. Through integrative analysis of chromatin contact
maps in 21 primary human … We also discover genomic regions that exhibit unusually high …

… We found that regions of accessible chromatin (ATAC-peaks) are co-accessible at kilobase
… chromatin organization measured by in situ Hi-C in T cells. Fifteen percent of genetic variants …

… Therefore, our study provides an accessible chromatin landscape of cartilage tissue for
better interpretation of other genetic and epigenomic data relevant to OA and other …

… that account for over 40% of the human genome 30 , and include long terminal repeats …
genes 31 , a systematic survey of the CA landscape of all of the retrotransposons during human …

… To systematically annotate candidate target genes for the cREs in the human genome,
we performed capture Hi-C experiments (Fig. 1a and Supplementary Fig. 1) to interrogate …