Aging of the immune system: focus on inflammation and vaccination

M Pinti, V Appay, J Campisi, D Frasca… - European journal of …, 2016 - Wiley Online Library
immune systems change with age, as discussed more extensively later in this review, the
phenotypes of these infiltrating immunevaccine-elicited antibody responses in the elderly, …

[HTML][HTML] Vaccination in the elderly: the challenge of immune changes with aging

A Ciabattini, C Nardini, F Santoro, P Garagnani… - Seminars in …, 2018 - Elsevier
elderly immune system and response to vaccination and we propose to focus on the relevance
of vaccine … the relevant molecular signatures of vaccine responses in the elderly. For this …

Influence of immune aging on vaccine responses

CE Gustafson, C Kim, CM Weyand… - Journal of Allergy and …, 2020 - Elsevier
… All modern vaccines work by tricking our immune system into developing “immunologic
memory” against a specific infectious pathogen. This immunologic memory is mediated by B and …

[HTML][HTML] Immunosenescence and human vaccine immune responses

SN Crooke, IG Ovsyannikova, GA Poland… - Immunity & …, 2019 - Springer
… personalized vaccine development (ie, vaccines developed … aging immune system and
highlighting promising approaches to further vaccine research efforts in support of healthy aging. …

Immunosenescence: A systems-level overview of immune cell biology and strategies for improving vaccine responses

SN Crooke, IG Ovsyannikova, GA Poland… - Experimental …, 2019 - Elsevier
… on the failure of the aging immune system, with an emphasis on … both the innate and adaptive
immune system, and we relate how … impact overall responses to infection and vaccination. …

[HTML][HTML] Targeting inflammation and immunosenescence to improve vaccine responses in the elderly

B Pereira, XN Xu, AN Akbar - Frontiers in immunology, 2020 - frontiersin.org
immune protection. In this review, we will describe the most recent data on the effects of aging
on immune responses to vaccinationimpact of an aging innate immune system in vaccine

Factors that influence the immune response to vaccination

P Zimmermann, N Curtis - Clinical microbiology reviews, 2019 - Am Soc Microbiol
Age is an important factor that influences vaccine responses, … Infants should receive
immunizations as early as possible to … vaccine in relation to the effect of age on vaccine

[HTML][HTML] Aging, immunity, and COVID-19: how age influences the host immune response to coronavirus infections?

V Bajaj, N Gadi, AP Spihlman, SC Wu, CH Choi… - Frontiers in …, 2021 - frontiersin.org
… to mount effective responses to vaccines. Immunosenescence and inflamm-… vaccine
approaches underway including antivirals and immune-modulating agents, and immune response

[HTML][HTML] Impact of aging and cytomegalovirus on immunological response to influenza vaccination and infection

S Merani, G Pawelec, GA Kuchel… - Frontiers in …, 2017 - frontiersin.org
… role in impaired influenza vaccine responses in older adults (34). … aging immune system
and CMV seropositivity both potentially hindering the immune response to influenza vaccination

[HTML][HTML] Age-related differences in humoral and cellular immune responses after primary immunisation: indications for stratified vaccination schedules

A Wagner, E Garner-Spitzer, J Jasinska, H Kollaritsch… - Scientific reports, 2018 - nature.com
responses are affected by primary vaccinations in the elderly population. Since the ageing
immune system … un-encountered vaccine antigens, as newly developed vaccines become …