[HTML][HTML] VLA-1 binding to collagen IV controls effector T cell suppression by myeloid-derived suppressor cells in the splenic red pulp

IN Eckert, E Ribechini, KJ Jarick, S Strozniak… - Frontiers in …, 2021 - frontiersin.org
… Together, our data point to a new role of VLA-1 adhesion to collagen IV as a prerequisite
for … The human integrin VLA-2 is a collagen receptor on some cells and a collagen/laminin

[PDF][PDF] Unconventional integrin-ligand interactions

K Sipilä - 2016 - utupub.fi
… integrins, ligand binding occurs via the homologous I domain … and laminins, but some cellular
receptors also bind directly to … We found that the adhesion of HUVEC cells to collagen I can …

[PDF][PDF] Activation Independent Functions of Collagen Receptor Integrins alpha1beta1 and alpha2beta1

M Salmela - 2017 - utupub.fi
that clustered α2β1-integrins can mediate Focal Adhesion … α7β1 are classified as laminin
binding integrins, but also the … homolog 1 and 2), numb, and filamin are inhibitory proteins …

Integrins α1β1 and α2β1: The Generalist Collagen Receptors

J Heino, E Siljamäki - Integrins in Health and Disease: Key Effectors of …, 2023 - Springer
… (VLA-1, VLA-2) (Hemler et al. 1985) and confirmed that both exist as … collagen gels, or cell
adhesion to fibrillar collagen may … that platelets also use other mechanisms to bind to collagen. …

Adhesion molecules in multiple myeloma oncogenesis and targeted therapy

M Bou Zerdan, L Nasr, J Kassab, L Saba… - International Journal …, 2022 - Future Medicine
… cells that are not identical, this binding is known as heterophilic … Riet et al., found a weak
expression of VLA-6 which is a laminin … molecule L-selectin and the collagen receptor VLA-2. …

[HTML][HTML] The molecular interaction of collagen with cell receptors for biological function

J Elango, C Hou, B Bao, S Wang… - Polymers, 2022 - mdpi.com
VLA-2, GPIa-IIa, and CD49b, was first identified as an extracellular matrix receptor for collagens
and/or laminins … claims that binding of collagen with discoidin-homology domain (DD) …

RGD cadherins and α2β1 integrin in cancer metastasis: a dangerous liaison

JI Casal, RA Bartolomé - Biochimica et Biophysica Acta (BBA)-Reviews on …, 2018 - Elsevier
… matrix, such as laminins, collagens and fibronectin (ie integrins… Both cadherins share a high
homology, including the RGD … authors described a 60% adhesion of platelets to recombinant …

[HTML][HTML] Regulatory mechanisms of neutrophil migration from the circulation to the airspace

WC Lin, MB Fessler - Cellular and Molecular Life Sciences, 2021 - Springer
… Arguing against an important role for molecular adhesion in steady-state PMN margination
that the CXCR4 antagonist AMD3100 demarginates PMNs from the lungs of mice and non-…

[HTML][HTML] Natural killer cell homing and trafficking in tissues and tumors: from biology to application

GH Ran, YQ Lin, L Tian, T Zhang, DM Yan… - Signal transduction and …, 2022 - nature.com
… ), and CD161 (the human homolog of the mouse NK1.1). The … , α2 (VLA-2)/β1, α4 (VLA-4)/β1,
and α5 (VLA-5)/β1 are critical … binding of α1/β1 to its partner collagen IV or laminin, or the …

Toll-like receptors and integrins crosstalk

F Alhamdan, G Bayarsaikhan, K Yuki - Frontiers in Immunology, 2024 - frontiersin.org
… Upon binding to fibronectin, collagen, and laminin, β1 … % of sequence homology to αMβ2
and about 50% of homology in … Multiple ligand binding functions for VLA-2 (alpha 2 beta 1) and …