[HTML][HTML] Tumor endothelial cells (TECs) as potential immune directors of the tumor microenvironment–new findings and future perspectives

L Nagl, L Horvath, A Pircher, D Wolf - … cell and developmental biology, 2020 - frontiersin.org
… to normal endothelial cells (NECs). Furthermore, the functional role of TECs is multifaceted
as they … The ultimate goal is the identification of TEC-specific drug targets to improve cancer (…

[HTML][HTML] Cancer stem cells (CSCs), circulating tumor cells (CTCs) and their interplay with cancer associated fibroblasts (CAFs): a new world of targets and treatments

B Aramini, V Masciale, C Arienti, M Dominici, F Stella… - Cancers, 2022 - mdpi.com
… Although with difficulties, the identification of new markers and … for the development of tailored
therapies against cancer. … both lung cancer growth and attract endothelial cells [106]. EVs …

[HTML][HTML] The role of sinusoidal endothelial cells in the axis of inflammation and cancer within the liver

AL Wilkinson, M Qurashi, S Shetty - Frontiers in physiology, 2020 - frontiersin.org
… surveillance against hepatotropic viral … marker and therefore, there is an urgent need to
understand how liver metastases develop, and subsequently identify potential therapeutic targets

Molecular phenotypes of endothelial cells in malignant tumors

V Milosevic, RJ Edelmann, JH Fosse, A Östman… - Biomarkers of the tumor …, 2022 - Springer
… protects against cytokine storm and related mortality [36]. … identification of tumor-derived
circulating endothelial cell … An approach for targeting pericytes has been proposed as well, …

[HTML][HTML] Circulating tumor cells from enumeration to analysis: Current challenges and future opportunities

YP Yang, TM Giret, RJ Cote - Cancers, 2021 - mdpi.com
… USA) against tumor-associated antigens from cancer cells of … identify cancer drivers for
diagnosis and therapeutic targets [101]… Circulating endothelial cells are other critical stromal cells

[HTML][HTML] Multifaceted roles of lymphatic and blood endothelial cells in the tumor microenvironment of hepatocellular carcinoma: A comprehensive review

JJ Li, JX Mao, HX Zhong, YY Zhao, F Teng… - World Journal of …, 2024 - ncbi.nlm.nih.gov
… (FGFR-3) has been identified as a novel PROX1 target gene. PROX1 induces the expression
… lymphatic endothelial cells (LECs) and enhance the migration of tumor cells towards LECs. …

[HTML][HTML] … strategies for preserving adult endothelium health and reversing its dysfunction: from liquid biopsy to new omics technologies and noninvasive circulating …

CR Balistreri - International journal of molecular sciences, 2022 - mdpi.com
… ECs via transcription factors (TFs) involved in endothelial cell … diverse regulator roles and
versatile cell actions of such molecules [… that defend against endothelial barrier dysfunction and …

[HTML][HTML] Heterogeneity of vascular endothelial cells, de novo arteriogenesis and therapeutic implications in pancreatic neuroendocrine tumors

B Ren, JB Rose, Y Liu, R Jaskular-Sztul… - Journal of Clinical …, 2019 - mdpi.com
… Angiopoietins, a multifaceted cytokine that functions in … but has limited action against stable
tumor vasculature [127]. … arteriogenesis in order to identify new targets for effective therapy. …

Platelet-coated circulating tumor cells are a predictive biomarker in patients with metastatic castrate-resistant prostate cancer

S Chai, N Matsumoto, R Storgard, CC Peng… - Molecular Cancer …, 2021 - AACR
… We aimed to identify circulating tumor cells (CTC) signatures … of cancer cells toward
mesenchymal or endothelial-like … the platelets, megakaryocytes, or endothelial cells (25). The …

[HTML][HTML] Comprehensive in situ co-detection of aneuploid circulating endothelial and tumor cells

PP Lin, O Gires, DD Wang, L Li, H Wang - Scientific reports, 2017 - nature.com
… methodologies are biased towards detection of the only … -hematopoietic aneuploid CD31 +
endothelial cells were detected for … CRCs, enables scientists to isolate intact single target cell