… These include studying roles of genetic factors in human aging and longevity… challenges
and internal aging-related changes. Several useful insights into the genetics of human longevity …

… recent insights into the genetics of extreme human longevity … identify genetic variants as
molecular targets for gaining insight … of the genetic factors that underlie extreme human lifespan …

… Insights into possible mechanisms of human longevity point to genetic and environmental
… important in differentiating genetic from environmental contributions to long life, and several …

… As human life expectancy is prolonged, age-related … data offer powerful insights into healthy
aging and longevity. For … Despite these issues, human epigenetic research using robust, …

… conserved aging mechanisms discovered in different model systems that are implicated
in human longevity as well and that could be the target of anti-aging interventions in human. …

… genetic determinants of healthspan and lifespan. Hopefully, … In the quest for human longevity
genes, genes involved in the … approaches for obtaining mechanistic insight into the process …

… in longevity and aging (sex hormones, immunity, genetic factors, … in longevity between males
and females, in human models … trend of increasing human life expectancy should persist. …

… features of APOE provides insight on the different behavior of … the genetic variants that
influence the longevity phenotype and … of the studies on human longevity conducted in relation to …

… an unprecedented rise in human life expectancy. Sustaining … Understanding the genetic
factors driving this variability in … , with these two sections providing insights into underlying DNA …

… The main challenge of longer lives will be to improve the potential for the extra years and …
, genetic variation within the FOXO3A gene was strongly associated with human longevity in …