Downregulation of plasma SELENBP1 protein in patients with recent-onset schizophrenia

EJ Chau, MS Mostaid, V Cropley, P McGorry… - Progress in Neuro …, 2018 - Elsevier
… In this study, we examined SELENBP1 mRNA expression in … utility of using SELENBP1
mRNA as a peripheral biomarker … results should to be replicated and validated in independent …

SELENBP1 overexpression in the prefrontal cortex underlies negative symptoms of schizophrenia

S Kim, SW Kim, MAT Bui, Y Kim… - Proceedings of the …, 2022 - National Acad Sciences
… abnormalities in EEG biomarkers observed in schizophrenia. … A subsequent study analyzing
gene expression in specific … To replicate earlier finding on the SELENBP1 upregulation in …

Transcriptional biomarkers of response to pharmacological treatments in severe mental disorders: A systematic review

C Pisanu, G Severino, I De Toma, M Dierssen… - European …, 2022 - Elsevier
… The most replicated results include genes playing a role in … of studies exploring the potential
utility and predictive value of … In particular, miRNAs negatively regulate gene expression

Brain, blood, cerebrospinal fluid, and serum biomarkers in schizophrenia

A Mohammadi, E Rashidi, VG Amooeian - Psychiatry research, 2018 - Elsevier
… levels of SELENBP1 and Glycogen synthase kinase 3 subunit α (GSK3α) genes in contrast
… However, most of the suggested models of Scz replicate mesolimbic dopamine dysfunction, …

Genomic predictors of remission to antidepressant treatment in geriatric depression using genome‐wide expression analyses: a pilot study

HA Eyre, A Eskin, SF Nelson, NM St. Cyr… - … journal of geriatric …, 2016 - Wiley Online Library
… We hypothesized that differential gene expression at … metabolic pathways and needs to be
replicated in a larger sample. … SELENBP1 is involved with selenium metabolism {Amar, 2010 #…

Genetic association between circulating selenium level and the risk of schizophrenia in the European population: A two-sample Mendelian randomization study

MG Deng, HT Cui, JQ Nie, Y Liang, C Chai - Frontiers in nutrition, 2022 - frontiersin.org
SELENBP1 mRNA in blood compared with controls (18). However, both downregulation and
upregulation of plasma SELENBP1 … No use, distribution or reproduction is permitted which …

[HTML][HTML] Biomarkers in schizophrenia: a focus on blood based diagnostics and theranostics

CY Lai, E Scarr, M Udawela, I Everall… - World journal of …, 2016 - ncbi.nlm.nih.gov
… because the dysregulation of gene expression, epigenetic patterns… as possible biomarkers
in Sz but most findings await replication. … Of these, SELENBP1 was identified as the strongest …

Selenium-binding protein 1 in human health and disease

M Elhodaky, AM Diamond - International journal of molecular sciences, 2018 - mdpi.com
… by gene expression microarrays indicated the increased expression of several genes associated
with … Less clear is why tumor suppressor genes such as Apc, RB1, and Trp53 were also …

Are essential trace elements effective in modulation of mental disorders? Update and perspectives

M Shayganfard - Biological Trace Element Research, 2022 - Springer
… of some viral diseases, and reproduction and defense against … by elevated cytokines
and biomarkers of cellular stress have … Environmental effects on gene expression may be a …

Cell-type specific analysis of selenium-related genes in brain

AR Sasuclark, VS Khadka, MW Pitts - Antioxidants, 2019 - mdpi.com
… Separate heatmaps of gene expression were generated for … We hypothesize that cytosolic
SELENBP1 may prevent Se from being … Of potential importance to neural Se homeostasis, we …