[HTML][HTML] Sex-specific associations of testosterone and genetic factors with health span

X Zhao, S Liang, N Wang, T Hong… - Frontiers in …, 2021 - frontiersin.org
… sex-specific associations that testosterone was negatively … both high genetic risk and abnormal
testosterone levels (high level in … the associations between testosterone and health span, …

Testosterone and lifespan in males: At the right time and the right level.

L Wang, H Yin, W Gu - Andrologia, 2022 - search.ebscohost.com
… law of lifespan (PLOSP) (Gu, 2022a, 2022b), the role of testosterone in the lifespan of males
may … Investigating the association of testosterone with survival in men and women using a …

The pharmaceuticalisation of 'healthy'ageing: Testosterone enhancement for longevity

M Dunn, KJD Mulrooney, C Forlini, K van de Ven… - International Journal of …, 2021 - Elsevier
… to testosterone replacement therapy (TRT). The non-medical use of testosterone can result
in a number of adverse health … Placing testosterone under a new prescribing regime may …

[HTML][HTML] Higher testosterone and testosterone/estradiol ratio in men are associated with better epigenetic estimators of mortality risk

CDJ Kusters, KC Paul, AT Lu, L Ferrucci, BR Ritz… - medRxiv, 2023 - ncbi.nlm.nih.gov
… While our study did not review the association between testosterone and mortality directly,
our results indicate that testosterone and the balance between testosterone and estradiol (TE …

Male and female gonadal ageing: Its impact on health span and life span

MB Frungieri, RS Calandra, A Bartke… - Mechanisms of Ageing …, 2021 - Elsevier
… in men and their association with male fertility is less clear. Male menopause, also called
andropause, is a gradual process clinically linked to declined testosterone levels, decreased …

[HTML][HTML] Investigating the association of testosterone with survival in men and women using a Mendelian randomization study in the UK Biobank

CM Schooling, JV Zhao - Scientific Reports, 2021 - nature.com
… the effects of testosterone were greater in … association study of life span or parental life span.
Such studies typically do not include the X chromosome, which is important for testosterone. …

Effects of testosterone supplementation on separate cognitive domains in cognitively healthy older men: a meta-analysis of current randomized clinical trials

S Tan, HR Sohrabi, M Weinborn, M Tegg… - The American Journal of …, 2019 - Elsevier
… Given the neuroprotective properties of T and its association with AD risk, researchers have
… In turn, use of spatial span tasks (eg, Corsi blocks tapping task) 57 may be a better measure …

Longitudinal changes in serum testosterone and sex hormone‐binding globulin in men aged 40–69 years from the UK Biobank

RJ Marriott, K Murray, GJ Hankey… - Clinical …, 2022 - Wiley Online Library
… of testosterone and SHBG are exposures of interest for investigating associations with
prospective health outcomes, we assessed for concordance in serum total testosterone and SHBG …

Associations of bioavailable serum testosterone with cognitive function in older men: results from the National Health and Nutrition Examination Survey

P Giannos, K Prokopidis, DD Church… - The Journals of …, 2023 - academic.oup.com
… function in older age may potentially have a meaningful impact on the development of
therapeutic interventions to improve patient treatment and outcome and extending the health span

Serum testosterone and cognitive function in ageing male: updating the evidence

VA Giagulli, E Guastamacchia… - Recent Patents on …, 2016 - ingentaconnect.com
… The association between endogenous free testosterone and cognitive performance: A
population-based study in 35 to 90 year-old men and women. Psychoneuroendocrinology 2006; …