… Herein, using cell sorting, RNA sequencing, in vitro studies … kidney development and
tumorigenesis; In nephrogenesis, NCAM1 + CD133 − marks SIX2 + multipotent renal stem cells …

… fetal kidneys remains limited. To address the key features of human fetal kidney development,
we applied single-cell RNA sequencing (scRNA-seq) to >3,000 renal cells spanning …

… There often exist heterogeneities at the cellular level that can only be dissected out with
high… In this article, we develop and test a cold protease method of single-cell dissociation, …

… cell populations was revealed, which may hide or skew signals of interest with specific cellular
identities and biologically-relevant mechanisms. Dissecting the … and develop new targeted …

… kidney development, we have used single-cell transcriptomics to characterize gene expression
in different cell populations, and to study individual cell … with which to dissect the gene …

… dissection, the metanephric rudiments are transferred onto a filter that floats on culture
medium and can be kept in a cell … several severe defects in kidney development, which were …

… in vitro tools to dissect the pathogenesis of diseases such as … the molecular basis of kidney
development will increase our … of pluripotent stem cells into clinically useful renal cells, and …

… of metanephric kidney development and provides a template … all component cell types during
mouse kidney development will … epithelium cell types from mouse and human cells for drug …

… We identified 22 cell types and a host of marker genes. … cells from five different developmental
ages, this study provides a rich resource for the elucidation of human kidney development, …

… to repair have been more challenging to dissect. Early analyses of the transcriptional … of
the location and cell types contributing to tubular repair in the mouse kidney. Rinkevich et al. …