… glomerular cells and sets the stage for the dissection of … in kidney disease, we tested
whether glomerular cell type … cell data, we used a previously developed algorithm to score …

… massively parallel single-cell RNA-sequencing (scRNA-seq) have been developed, in which
the … scRNA-seq is uniquely well suited to dissecting a complex tissue into multiple cellular …

… an understanding of kidney development and disease and enhance efforts to generate new
… events or cell types. Although single-cell-omic approaches now facilitate the dissection and …

… develop fibrosis and chronic kidney disease. Interactions between injured epithelia, stroma,
and inflammatory cells determine whether kidneys … allowed the molecular dissection of ligand…

… To dissect the role of Jag-Notch in collecting cell development at higher resolution, we … the
GFP-labeled knockout cells. We found an increase in ‘double positive cells’ (from 2% to 12%, …

… Dnmbp protein is present in whole embryo lysates starting in single cell embryos and
continuing throughout kidney development. In situ hybridization showed that dnmbp transcripts are …

… (G) Proportional contribution of fetal developing nephron cell types at distinct … To explore
the spatial distribution of these cells across the kidney, we sought to assign a depth estimate of …

… to the developing mouse kidney 6 . Similar results have not been reproduced using human
cells. Recent … Kidneys were then isolated by manual dissection and dissociated into single …

… obstruction model to dissect the transcriptomic landscape at the single-cell level during renal
… Differential proportion analysis was developed to detect changes in population proportions …

… Thus, a comparative study of kidney development and continual … and maintain nephrogenic
progenitor cell pools. Such study may … Tissue from freshly dissected kidneys was fixed in 4% …