How many cell types are in the kidney and what do they do?

MS Balzer, T Rohacs, K Susztak - Annual review of physiology, 2022 - annualreviews.org
… and genetic cell type definition with remarkable precision. Here, we discuss how each
kidney cell type has specialized to achieve this complex function, how an individual cell's gene …

[HTML][HTML] Defining the variety of cell types in developing and adult human kidneys by single-cell RNA sequencing

A Schumacher, MB Rookmaaker, JA Joles… - NPJ Regenerative …, 2021 - nature.com
human renal cell types, we discuss research that used single-cell RNA sequencing on
developing and adult human … of renal cell types in the developing and adult human kidney by …

Mapping the genetic architecture of human traits to cell types in the kidney identifies mechanisms of disease and potential treatments

X Sheng, Y Guan, Z Ma, J Wu, H Liu, C Qiu, S Vitale… - Nature …, 2021 - nature.com
… To estimate the sharing of cell type eQTL(ci)s across different cell types in each kidney
compartment, we adopted a multivariate adaptive shrinkage method (mash) 41 and followed the …

Mapping the human kidney using single-cell genomics

F Schreibing, R Kramann - Nature Reviews Nephrology, 2022 - nature.com
cells. Insights into the phenotypic diversity of kidney endothelial and kidney-resident immune
cells has been reviewed elsewhere 34,35 , and so here we focus mainly on the cellular

[HTML][HTML] Single-cell RNA sequencing of human kidney

J Liao, Z Yu, Y Chen, M Bao, C Zou, H Zhang, D Liu… - Scientific data, 2020 - nature.com
… -specific, especially renal tubular cells. To investigate the classification and … the human
kidney, we rapidly obtained a single-cell suspension of the kidney and conducted single-cell RNA …

[HTML][HTML] An atlas of healthy and injured cell states and niches in the human kidney

BB Lake, R Menon, S Winfree, Q Hu, R Melo Ferreira… - Nature, 2023 - nature.com
… complexity for all cell types along the depth of the kidney from the … human kidney cell types
with associated biomarkers (Methods and Supplementary Tables 5−8). This includes cell type

In situ classification of cell types in human kidney tissue using 3D nuclear staining

A Woloshuk, S Khochare, AF Almulhim… - Cytometry Part …, 2021 - Wiley Online Library
… a cell type label. We then devised various supervised machine learning approaches for kidney
cell … allowed in situ visualization of cell type classifications in kidney tissue. In conclusion, …

Single-cell transcriptomics of a human kidney allograft biopsy specimen defines a diverse inflammatory response

H Wu, AF Malone, EL Donnelly, Y Kirita… - Journal of the …, 2018 - journals.lww.com
… -seq analysis of a single human kidney allograft biopsy. We used … cell types and novel cell
states within endothelium. We compared tubular cell transcriptomes with healthy adult kidney

[HTML][HTML] Single-cell analysis reveals congruence between kidney organoids and human fetal kidney

AN Combes, L Zappia, PX Er, A Oshlack, MH Little - Genome medicine, 2019 - Springer
human kidney cell types [55]. While the renal populations and congruence with human kidney
cell types … results, the relative proportion and types of cells captured by that analysis differs …

[HTML][HTML] Immune cell composition in normal human kidneys

JG Park, M Na, MG Kim, SH Park, HJ Lee, DK Kim… - Scientific Reports, 2020 - nature.com
… Subsequently, human kidney immune cell subsets were analysed using multicolor flow …
whether human kidneys harboured different immune cell subsets from mouse kidneys. Of …