Oral antiviral treatments for COVID-19: opportunities and challenges

L Rahmah, SO Abarikwu, AG Arero, M Essouma… - Pharmacological …, 2022 - Springer
… -2 oral drugs (nirmatrelvir/ritonavir and molnupiravir), (iii) summarizes the clinical progress of
other oral antivirals for use in COVID-19, (iv… with the use of oral antivirals in clinical practice. …

Molnupiravir, an oral antiviral treatment for COVID-19

W Fischer, JJ Eron Jr, W Holman, MS Cohen, L Fang… - MedRxiv, 2021 - medrxiv.org
… distributed oral antivirals are urgently needed to treat coronavirus disease-2019 (COVID-19), …
, and block transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)…

Efficacy and safety of three new oral antiviral treatment (molnupiravir, fluvoxamine and Paxlovid) for COVID-19: a meta-analysis

W Wen, C Chen, J Tang, C Wang, M Zhou… - Annals of …, 2022 - Taylor & Francis
… made in COVID-19 research and many antiviral drugs have … against COVID-19, a simple
oral antiviral drug for COVID-19 has … among COVID-19 patients with three new oral antivirals (…

Antivirals and the potential benefits of orally inhaled drug administration in COVID-19 treatment

G Sahin, O Akbal-Dagistan, M Culha, A Erturk… - Journal of …, 2022 - Elsevier
… This review aims to summarize ongoing antiviral treatments in COVID-19, to discuss …
COVID-19) evaluating oral antiviral Favipiravir's at home use for mild-to-moderate COVID-19

The role of antiviral treatment in the COVID-19 pandemic

TK Burki - The Lancet Respiratory Medicine, 2022 - thelancet.com
… “The oral antivirals do not have the complications of the … be the most widely available antiviral
for COVID-19. Paxlovid is a … order of 50 000 doses of the antiviral—the interim results had …

The first Chinese oral anti-COVID-19 drug Azvudine launched

B Yu, J Chang - The Innovation, 2022 - cell.com
… -based antiviral agents could be repurposed for COVID-19 treatment. … COVID-19 epidemic
and is potentially to be used to treat future coronavirus infections as well as other coronavirus-…

Impact of the use of oral antiviral agents on the risk of hospitalization in community coronavirus disease 2019 patients (COVID-19)

TCF Yip, GCY Lui, MSM Lai, VWS Wong… - Clinical infectious …, 2023 - academic.oup.com
… 2 COVID-19 oral antivirals amid the peak of an outbreak with omicron variant infections in a
densely populated city. Compared with no antiviral … patients with COVID-19. Neither of the …

Molnupiravir for oral treatment of Covid-19 in nonhospitalized patients

A Jayk Bernal, MM Gomes da Silva… - … England Journal of …, 2022 - Mass Medical Soc
… New treatments are needed to reduce the risk of progression of coronavirus disease 2019
(Covid-19). Molnupiravir is an oral, small-molecule antiviral prodrug that is active against …

[HTML][HTML] The emergence of powerful oral anti-COVID-19 drugs in the post-vaccine era

H Fan, F Lou, J Fan, M Li, Y Tong - The Lancet Microbe, 2022 - thelancet.com
… —the development of oral antiviral treatment for COVID-19 still needs further study. In addition
to molnupiravir, four more oral anti-COVID-19 drugs are in phase 3 clinical trials: the 3CL …

Oral antiviral treatment for COVID-19: a comprehensive review on nirmatrelvir/ritonavir

K Akinosoglou, G Schinas, C Gogos - Viruses, 2022 - mdpi.com
… Despite this breakthrough, COVID-19 will constitute an enduring public health issue [8]. …
oral alternatives [15]. In early 2021, EMA approved the first oral antiviral against COVID-19, ie, …