The potential of JAK/STAT pathway inhibition by ruxolitinib in the treatment of COVID-19

BG Bagca, CB Avci - Cytokine & growth factor reviews, 2020 - Elsevier
… / STAT signaling pathway, one of the critical cellular signaling pathways involved in the
inflammatory response. This review presents an overview of SARS-CoV-2 and the COVID-19

[HTML][HTML] COVID-19 and Parkinson's disease: shared inflammatory pathways under oxidative stress

ZL Chaudhry, D Klenja, N Janjua, G Cami-Kobeci… - Brain Sciences, 2020 - mdpi.com
… Taken together, our study of the NFκB signalling pathway in the … signalling cascade may
be a common inflammatory pathway observed in the pathogenesis of both PD and COVID-19. …

Potential mechanism underlying the effect of matrine on COVID-19 patients revealed through network pharmacological approaches and molecular docking analysis

W Peng, Y Xu, D Han, F Feng, Z Wang… - … of Physiology and …, 2023 - Taylor & Francis
… SARS-CoV-2 and help alleviate COVID-19, our data further report that matrine probably
targets TNF, IL-6, and CASP3 via the TNF signalling pathway. TNF is secreted by activated …

Unveiling COVID-19-associated organ-specific cell types and cell-specific pathway cascade

A Dey, S Sen, U Maulik - Briefings in bioinformatics, 2021 - academic.oup.com
… connectivity associating with ACE2 dysregulation during COVID-19 infection. Initially, we …
infections like COVID-19. In this experiment, the impact of PPAR signalling pathways and RAS …

[HTML][HTML] The COVID-19-diabetes mellitus molecular tetrahedron

M Mahmudpour, K Vahdat, M Keshavarz… - Molecular Biology …, 2022 - Springer
pathways and potential hubs for pathogenesis of COVID-19-induced new-onset diabetes
based on the reported transcriptional and proteomic data from COVID-19signaling pathways, …

Exploring the treatment of COVID19 with Yinqiao powder based on network pharmacology

H Lin, X Wang, M Liu, M Huang, Z Shen… - Phytotherapy …, 2021 - Wiley Online Library
… of COVID-19 are the TNF signaling pathway, T-cell receptor … signaling pathway. This
study provides a new perspective for discovering potential drugs and mechanisms of COVID-19. …

[引用][C] Platelet activation via PI3K/AKT signaling pathway in COVID-19

L Pelzl, A Singh, J Funk, A Witzemann, J Zlamal… - Research and practice in …, 2021

Network pharmacology and molecular docking analysis on molecular targets and mechanisms of Huashi Baidu formula in the treatment of COVID-19

Q Tao, J Du, X Li, J Zeng, B Tan, J Xu… - Drug development and …, 2020 - Taylor & Francis
… Quercetin was found to regulate the activation of MAPK signaling pathway in … MAPK
signaling pathway [Citation50]. (3) PI3K–Akt signaling pathway: The PI3K/AKT signaling pathway

[HTML][HTML] Analyzing the potential therapeutic mechanism of Huashi Baidu Decoction on severe COVID-19 through integrating network pharmacological methods

YW Zhu, XF Yan, TJ Ye, J Hu, XL Wang, FJ Qiu… - Journal of traditional and …, 2021 - Elsevier
… NOD-like receptor signaling pathways by which HSBD treats severe COVID-19, indicating
that it may be the most important therapeutic active compound of HSBD on severe COVID-19. …

[HTML][HTML] A hypothesis for the possible role of zinc in the immunological pathways related to COVID-19 infection

A Mayor-Ibarguren, C Busca-Arenzana… - Frontiers in …, 2020 - frontiersin.org
… Legend: A schematic view of the involvement of zinc in various signaling pathways.
Green arrows: zinc-mediated activation. Red T bar arrows: zinc-mediated inhibition. …