The 'cytokine storm': molecular mechanisms and therapeutic prospects

R Karki, TD Kanneganti - Trends in immunology, 2021 - cell.com
molecular mechanisms is lacking. Recent studies demonstrate a positive feedback loop …
cytokine release and cell death pathways; certain cytokines, pathogen-associated molecular

… cytokines in COVID-19 patients: A review on molecular mechanisms, immune functions, immunopathology and immunomodulatory drugs to counter cytokine storm

AA Rabaan, SH Al-Ahmed, J Muhammad, A Khan… - Vaccines, 2021 - mdpi.com
… and dysfunctional cytokines response as some cytokines are … light on the molecular
mechanisms of the cytokines and their … to control and treat the cytokine storm or hypercytokinemia …

Cytokine storm—definition, causes, and implications

D Jarczak, A Nierhaus - International journal of molecular sciences, 2022 - mdpi.com
… If the inflammatory reaction is very pronounced, an ultimately uncontrolled release of
proinflammatory cytokines leads to cytokine storm with the known potentially lethal courses [168]. …

Modeling and simulations of CoViD-19 molecular mechanism induced by cytokines storm during SARS-CoV2 infection

Z Yu, R Ellahi, A Nutini, A Sohail, SM Sait - Journal of molecular liquids, 2021 - Elsevier
… Different computational models based on the molecular mechanism of the said problems,
are available in the literature [[14], [15], [16], [17]]. During this research, we developed a model …

Highways to hell: Mechanism-based management of cytokine storm syndromes

SW Canna, RQ Cron - Journal of Allergy and Clinical Immunology, 2020 - Elsevier
… these mechanisms interact and overlap. Likewise, the utility of a broad term such as “cytokine
storm” is … CSS research must improve our appreciation of its various mechanisms and their …

Cytokine storm induced by SARS-CoV-2

P Song, W Li, J Xie, Y Hou, C You - Clinica chimica acta, 2020 - Elsevier
… Pieces of evidence from current studies have shown that the cytokine storm may be an …
profile, the molecular mechanisms of the SARS-CoV-2-induced cytokine storm and immune …

Cytokine storm in COVID-19—immunopathological mechanisms, clinical considerations, and therapeutic approaches: the REPROGRAM consortium position paper

S Bhaskar, A Sinha, M Banach, S Mittoo… - Frontiers in …, 2020 - frontiersin.org
… Understanding the pathogenesis of cytokine storm will help … In this article, we present an
overview of the cytokine storm and … paper provides critical insights on cytokine storm from both a …

Innate immunity, cytokine storm, and inflammatory cell death in COVID-19

R Karki, TD Kanneganti - Journal of Translational Medicine, 2022 - Springer
… These processes can contribute to cytokine storm, tissue … cytokine storm and organ
damage in patients with severe COVID-19. A better understanding of the molecular mechanisms

The cytokine storm in COVID-19: An overview of the involvement of the chemokine/chemokine-receptor system

F Coperchini, L Chiovato, L Croce, F Magri… - Cytokine & growth factor …, 2020 - Elsevier
… This review will be aimed at providing an overview of the current knowledge on the involvement
of the chemokine/chemokine-receptor system in the cytokine storm related to SARS-CoV…

From anti-SARS-CoV-2 immune response to the cytokine storm via molecular mimicry

D Kanduc - Antibodies, 2021 - mdpi.com
… role of molecular mimicry in the cytokine storms associated … , can lead to cytokine storms
characterized by diverse disorders … The molecular mechanisms that subvert a beneficial innate …