Patient characteristics, clinical outcomes, and effect of dapagliflozin in relation to duration of heart failure: is it ever too late to start a new therapy?

SE Yeoh, P Dewan, PS Jhund, SE Inzucchi… - … : Heart Failure, 2020 - Am Heart Assoc
… ejection fraction (LVEF) ≤40%, an elevated natriuretic peptide level and were receiving
optimal HFrEF pharmacological and device therapy, according to local guidelines. …

Effect of dapagliflozin on indicators of myocardial fibrosis and levels of inflammatory factors in heart failure patients

C Wang, Y Qin, X Zhang, Y Yang, X Wu, J Liu… - Disease …, 2022 - Wiley Online Library
… b-type natriuretic peptide (BNP) were detected in the department of laboratory. The level
of monocyte chemoattractant protein-1 (MCP-1) in serum was detected using enzyme-linked …

Natriuretic effect of two weeks of dapagliflozin treatment in patients with type 2 diabetes and preserved kidney function during standardized sodium intake: results of …

RA Scholtes, MHA Muskiet, MJB van Baar… - Diabetes …, 2021 - Am Diabetes Assoc
… N-terminal pro-B-type natriuretic peptide (NT-proBNP) were … with dapagliflozin in patients
who had no heart failure or … volume observed in a prior study with dapagliflozin (12). In addition…

Effect of dapagliflozin on cardiac function in people with type 2 diabetes and albuminuria–A double blind randomized placebo-controlled crossover trial

MK Eickhoff, FJ Olsen, M Frimodt-Møller, LJ Diaz… - Journal of Diabetes and …, 2020 - Elsevier
… of heart failure (HF) and cardiovascular death in people with type 2 diabetes (T2D) and …
cardiovascular disease. Our aim was to examine the effect of the SGLT2i dapagliflozin on cardiac

… in characteristics, outcomes, and treatment response with dapagliflozin across the range of ejection fraction in patients with heart failure: insights from DAPA-HF and …

X Wang, M Vaduganathan, BL Claggett, SM Hegde… - Circulation, 2023 - Am Heart Assoc
… ≥40 years of age with chronic NYHA class II to IV HF, LVEF >40%, structural heart disease
(… in natriuretic peptides. In both trials, patients were randomized to receive dapagliflozin 10 …

Efficacy and safety of dapagliflozin according to frailty in patients with heart failure: a prespecified analysis of the DELIVER trial

JH Butt, PS Jhund, J Belohlávek, RA De Boer… - Circulation, 2022 - Am Heart Assoc
… %, evidence of structural heart disease (either left atrial enlargement or left ventricular
hypertrophy), and NT-proBNP (N-terminal pro–B-type natriuretic peptide) concentration ≥300 pg/…

Dapagliflozin in heart failure with mildly reduced or preserved ejection fraction according to polypharmacy status

A Peikert, P Goyal, M Vaduganathan, BL Claggett… - Heart Failure, 2023 - jacc.org
… >40%, elevated N-terminal pro–B-type natriuretic peptide (NT-proBNP) levels (≥300 pg/mL …
structural heart disease (left atrial enlargement or left ventricular hypertrophy). Patients with …

Prediction of the effect of dapagliflozin on kidney and heart failure outcomes based on short-term changes in multiple risk markers

NMA Idzerda, BV Stefansson, MJ Pena… - Nephrology Dialysis …, 2020 - academic.oup.com
… For example, we ideally would have used N-terminal prohormone of brain natriuretic peptide
as a marker for volume status instead of body weight, as the latter may merely represent …

[HTML][HTML] Natriuretic Peptide–Based Risk Prediction and Assessment of Treatment Effect: Revisited in This Era

A Tanaka, K Node - Heart Failure, 2021 - jacc.org
Natriuretic peptide (NP) levels, such as those of N-terminal pro–B-type NP (NT-proBNP), …
of heart failure (HF) and its risk prediction. However, NP values are often modified by cardiac

Dapagliflozin and kidney outcomes in patients with heart failure with mildly reduced or preserved ejection fraction: a prespecified analysis of the DELIVER randomized …

FR Mc Causland, BL Claggett, M Vaduganathan… - JAMA …, 2023 - jamanetwork.com
Dapagliflozin in heart failure with mildly reduced or preserved ejection fraction.  …
ejection fraction greater than 40%, elevated N-terminal pro–brain natriuretic peptide (NT-proBNP) …