[HTML][HTML] Cystic fibrosis in young children: a review of disease manifestation, progression, and response to early treatment

DR VanDevanter, JS Kahle, AK O'Sullivan… - … of Cystic Fibrosis, 2016 - Elsevier
… Studies have described illness associated with cystic fibrosis (CF) early in life, but there
is no comprehensive accounting of the prevalence and ages of disease manifestation and …

Early diagnosis and intervention in cystic fibrosis: imagining the unimaginable

AM Coverstone, TW Ferkol - Frontiers in Pediatrics, 2021 - frontiersin.org
… Newborn screening programs for cystic fibrosis are now implemented throughout … Early
diagnosis and interventions have led to improved clinical outcomes for people with cystic fibrosis

The cumulative effect of inflammation and infection on structural lung disease in early cystic fibrosis

T Rosenow, LC Mok, L Turkovic… - European …, 2019 - Eur Respiratory Soc
… Lung disease in cystic fibrosis (CF) begins early in life and is characterised by an ongoing
… treatment for early CF lung disease would be warranted. Optimising early intervention and …

[HTML][HTML] Early diagnosis from newborn screening maximises survival in severe cystic fibrosis

G Tridello, C Castellani, I Meneghelli… - ERJ open …, 2018 - Eur Respiratory Soc
cystic fibrosis (CF) have been implemented since the early … that presymptomatic detection
permits early access to specialised … In fact, several benefits have been associated with early

Does newborn screening improve early lung function in cystic fibrosis?

G Davies - Paediatric Respiratory Reviews, 2022 - Elsevier
… It will describe how we measure early lung … cystic fibrosis transmembrane conductance
regulator (CFTR) modulator therapy (HEMT). Although this current review focuses on early lung …

Cystic fibrosis: a clinical view

C Castellani, BM Assael - Cellular and molecular life sciences, 2017 - Springer
Cystic fibrosis (CF), a monogenic disease caused by mutations in the CFTR gene on … years
of age, mainly thanks to the early diagnosis through neonatal screening, recognition of mild …

Structural determinants of long-term functional outcomes in young children with cystic fibrosis

L Turkovic, D Caudri, T Rosenow… - European …, 2020 - Eur Respiratory Soc
… surrogate end-point in early intervention trials, is trying to … -term effects might be expected
from an intervention in early life when … Respiratory Early Surveillance Team for Cystic Fibrosis (…

[HTML][HTML] Development of the gut microbiota in early life: The impact of cystic fibrosis and antibiotic treatment

M Kristensen, SMPJ Prevaes, G Kalkman… - … of Cystic Fibrosis, 2020 - Elsevier
… Patients with Cystic Fibrosis (CF) … early life development of the gut microbial community
composition of children with CF compared to healthy infants and to study the independent effects

Early lung disease in infants and preschool children with cystic fibrosis. What have we learned and what should we do about it?

SC Ranganathan, GL Hall, PD Sly, SM Stick… - American journal of …, 2017 - atsjournals.org
… in cystic fibrosis (CF). Pulmonary inflammation, infection, and structural lung damage manifest
very earlyEarly childhood represents a pivotal period amenable to intervention strategies …

Best practices in the treatment of early cystic fibrosis lung disease

M Proesmans - Therapeutic advances in respiratory disease, 2017 - journals.sagepub.com
early because lung damage occurs in young patients, often before obvious symptoms appear.
The arrival of new cystic fibrosis … In this overview, the literature is reviewed on early stage …