eggNOG 4.5: a hierarchical orthology framework with improved functional annotations for eukaryotic, prokaryotic and viral sequences

J Huerta-Cepas, D Szklarczyk, K Forslund… - Nucleic acids …, 2016 - academic.oup.com
… for creating OGs across taxonomic levels, making nested groups hierarchically … eggNOG
to infer pairwise orthology mappings. Finally, users can provide a list of target organisms, or …

A Bayesian inference method for the analysis of transcriptional regulatory networks in metagenomic data

ET Hobbs, T Pereira, PK O'Neill, I Erill - Algorithms for Molecular Biology, 2016 - Springer
… that reported in studies on model organisms, outlining the core … of orthologous groups defined
in the eggNOG database, … Bayesian inference to compute the probability that an eggNOG/…

Tree reconciliation combined with subsampling improves large scale inference of orthologous group hierarchies

D Heller, D Szklarczyk, C Mering - BMC bioinformatics, 2019 - Springer
… version 4.0 of the eggNOG database [23], which provides non-supervised orthologous groups
for 2031 species across … of nested taxonomic levels, in this example from Saccharomyceta …

Identification of microbiota biomarkers with orthologous gene annotation for type 2 diabetes

YH Zhang, W Guo, T Zeng, SQ Zhang, L Chen… - Frontiers in …, 2021 - frontiersin.org
… we first introduced eggNOG database and KEGG ORTHOLOGY (KO) database for orthologous
(… is typically a hypothetical protein, the organisms from which such protein is derived from …

Construction of a Full-Length Transcriptome of Western Honeybee Midgut Tissue and Improved Genome Annotation

H Zang, S Guo, S Dong, Y Song, K Li, X Fan, J Qiu… - Genes, 2024 - mdpi.com
… of animals, plants, and microorganisms such as … ) (Table 4 and Table S1, Figure 1B). In
addition, 41,771 full-length transcripts were annotated to 25 functional categories in the eggNOG

Homology inference based on a reconciliation approach for the comparative genomics of Protozoa

DA Campos, EC Pereira, R Jardim… - Evolutionary …, 2018 - journals.sagepub.com
orthologous groups: 1481 (OrthoMCL) versus 1231 (OMA). Taking as reference only the
orthologous groups shared by the 3 organisms of … invadens was the organism with the highest …

Trait biases in microbial reference genomes

S Albright, S Louca - Scientific Data, 2023 - nature.com
eggNOG MPRs were substantially smaller than KEGG MPRs in 3 out of 6 environments (human,
other animals … on the organism having or lacking a specific gene (KEGG ortholog). For …

[PDF][PDF] Comparative Analysis of Ortholog and Paralog Detection

P Bhambri, OP Gupta - … Journal of Research in Engineering, IT and …, 2017 - indusedu.org
… There are number of methods used to infer orthology and paralogy. … to previous release of
EggNOG, V4 contains tripled the underlying species set to cover 3686 organisms. It also gives …

OrthoFinder: phylogenetic orthology inference for comparative genomics

DM Emms, S Kelly - Genome biology, 2019 - Springer
… of biological knowledge between organisms. Given the … through heuristic analyses of
pairwise sequence similarity scores (or expectation values) obtained from an all-vs-all BLAST [4] …

Metagenomic analysis identifies sex-related Cecal microbial gene functions and bacterial taxa in the quail

JE Ma, XW Xiong, JG Xu, JS Gong, J Li, Q Xu… - Frontiers in Veterinary …, 2021 - frontiersin.org
… the male animals had high abundances of Bacteroides, whereas female animals were enriched
… separately via BLAST against the KEGG, EggNOG, CAZy, and CARD databases using …