[HTML][HTML] SARS-CoV-2 evolution in an immunocompromised host reveals shared neutralization escape mechanisms

SA Clark, LE Clark, J Pan, A Coscia, LGA McKay… - Cell, 2021 - cell.com
… escape caused by S changes that occurred in the immunocompromised host. Notably, the
S mutations we studied foreshadowed the appearance of emerging SARS-CoV-2 variants. …

SARS-CoV-2 in immunocompromised individuals

S DeWolf, JC Laracy, MA Perales, M Kamboj… - Immunity, 2022 - cell.com
Immunocompromised individuals and particularly those with hematologic malignancies are
at increased risk for SARS-CoV-… states of immunologic vulnerability to SARS-CoV-2 and how …

Long-term SARS-CoV-2 asymptomatic carriage in an immunocompromised host: clinical, immunological, and virological implications

M Spinicci, A Mazzoni, M Coppi, A Antonelli… - Journal of clinical …, 2022 - Springer
Purpose SARS-CoV-2 infection in immunocompromised hosts is challenging, and prolonged
viral shedding can be a common complication in these patients. We describe the clinical, …

Comprehensive analysis of disease pathology in immunocompetent and immunocompromised hosts following pulmonary SARS-CoV-2 infection

S Ramasamy, A Kolloli, R Kumar, S Husain… - Biomedicines, 2022 - mdpi.com
immunocompromised hosts during SARS-CoV-2 infection is not fully understood. We used a
hamster model of SARS-CoV… 19, to determine the dynamics of SARS-CoV-2 replication and …

Coronavirus disease-2019 in the immunocompromised host

CD Bertini, F Khawaja… - Clinics in Chest …, 2023 - chestmed.theclinics.com
… Of note, 23% of patients with hematologic malignancy had no detectable anti-SARS-CoV-2
T-cell responses. In another cohort of 79 COVID-19 patients, 36 immunocompromised hosts

Persistence and evolution of SARS-CoV-2 in an immunocompromised host

B Choi, MC Choudhary, J Regan… - … England Journal of …, 2020 - Mass Medical Soc
… nasopharyngeal and bronchoalveolar-lavage SARS-CoV-2 RT-… immunocompromised
persons effectively clear SARS-CoV-2 … evolution associated with an immunocompromised state. …

The immunocompromised transplant recipient and SARS-CoV-2 infection

JA Fishman - Journal of the American Society of Nephrology, 2020 - journals.lww.com
… We assume that, for each pathogen, the immunocompromised host will demonstrate reduced
resistance to infection, atypical clinical signs and symptoms, more rapid progression, and …

Monitoring and managing SARS-CoV-2 evolution in immunocompromised populations

P Li, AC de Vries, N Kamar, MP Peppelenbosch… - The Lancet …, 2022 - thelancet.com
… Since the start of the COVID-19 pandemic in late 2019, five SARS-CoV-2 variants of concern
SARS-CoV-2 infection in immunocompromised populations might propagate SARS-CoV-2 …

[HTML][HTML] SARS-CoV-2 intra-host evolution during prolonged infection in an immunocompromised patient

EG Quaranta, A Fusaro, E Giussani, V D'Amico… - International Journal of …, 2022 - Elsevier
… : Intra-host SARS-CoV-2 evolution during chronic infection in immunocompromised hosts
has … Methods: Using a deep sequencing approach, we investigated the SARS-CoV-2 intra-host

[HTML][HTML] Case study: prolonged infectious SARS-CoV-2 shedding from an asymptomatic immunocompromised individual with cancer

VA Avanzato, MJ Matson, SN Seifert, R Pryce… - Cell, 2020 - cell.com
… , SARS-CoV-2 RNA was no longer detected. We observed marked within-host genomic
evolution of SARS-CoV… Our data indicate that certain immunocompromised individuals may shed …