Our understanding of the genetic basis of cardiovascular diseases (CVDs) has evolved
rapidly. This has resulted from a combination of dedicated research in well phenotyped CVD …

… et al; American College of Medical Genetics and Genomics. ACMG recommendations for …
(low likelihood of positive genetic test results and a low predicted clinical effect) and should be …

… Mortality and morbidity from cardiovascular diseases (CVDs) represents a huge burden to …
in disease susceptibility, but the link between these external risk factors and our genetics has …

… outcomes beyond the development of the structural heart disease. Progress in the … They
also have potential clinical implications. It is possible to imagine a clinical genetic test that can …

… undergone clinical genetic testing or who underwent clinical genetic testing after receiving
… to the heterogeneous genetic etiology of inherited cardiovascular diseases. Because there …

… but their clinical effect and adverse effect profile may … genetic risk for coronary artery disease,
the adoption of healthy lifestyle habits can reduce the relative risk of coronary heart disease …

… to understand the genetic drivers of CAD, the role of human genetics in catalysing CAD drug
… that influence the biomarker or risk of coronary artery disease (CAD); and any impact of the …

… familial heart disease with vast genetic heterogeneity. Mutations in 11 or more genes encoding
proteins of the cardiac … risk of cardiovascular disease (CVD) or with strong effect on CVD …

… highest genetic risk category, with highly significant effects on … CAD risk beyond traditional
risk factors and may have both clinical … disease-deferring therapies, including statin treatment. …

… In conclusion, we observed no major effect of communicating genetic risk for CAD on risk-reducing
health behaviors. The potential benefits in weight loss and physical activity for …