… While the reductionist approach has led directly to remarkable advances in contemporary
cell and molecular biology, the exclusion of environmental factors from most studies removed …

… pathways involved in kidney development. The creation of kidney organoids from hPSCs
by … has also expanded our knowledge of kidney development. Organoids can be generated …

… kidney development comes from studies of only two mammals: the rat and mouse. Development
is … A broad overview of kidney development in the mouse is followed by a more detailed …

… Normal kidney development is realised through the actions of … are required for the normal
development of the organ. Genetic … deficiency and congenital defects in kidney development. …

… In summary, elucidating the molecular basis of kidney development will increase our
understanding of renal birth defects and disease, provide a foundation for directing the …

… Upon induction of β-catenin activity in these cells with a small molecule BIO, which mimics
canonical Wnt signaling response, expression of E-cadherin (indicator of epithelialization), …

… the serious relationship between kidney development and drug … , has been proven safe to
use during renal development”65. … Molecular development of the kidney: a review of the results …

… The power of genetics and molecular biology in model organisms has greatly advanced our
… The precise regression of the mesonephroi is critical for normal kidney development, and …

… kidney organoid technology, especially focusing on the relationship to the study of human
kidney development, … cell cultures to investigate the molecular pathogenesis ex vivo. However, …

… regulate kidney development and lead to the formation of functional nephrons. We will further
focus on ECM deposition during kidney development. … Signaling in kidney development …