… antibodies and T-cell therapies has rapidly evolved, and CRS can be a serious adverse …
a cytokine storm (Figure 1). However, the pathophysiology of CRS is still poorly understood. …

… Cytokine storm is a severe and damaging immune reaction … production of pro-inflammatory
cytokines. This term has … The pathophysiological mechanisms underlying the cytokine …

… immune responses with a more severe cytokine storm, increased infiltration of CD11b + cells,
… Thus, the delayed but more severe cytokine storm and higher immune cell infiltration may …

… Most animals require sleep, and sleep loss induces serious pathophysiological … both
accumulation of circulating neutrophils and a cytokine-storm-like syndrome. Experimental disruption …

… the unpredictability of viral evolution pose a major challenge … Cytokine storm (CS) was
associated with many of these RNA … detection of the pathophysiological conditions of patients as …

… secondary organ dysfunction, an evolving challenge often requiring multidisciplinary care. …
, have thus far yielded few insights into the pathophysiology of MIS-C. Severe cases of MIS-C …

… of pro-inflammatory cytokines and chemokines (refer to Innate immunity under host immune
response section) is called a “cytokine storm.” This cytokine storm triggers a violent attack to …

… Genome-envelope viruses are continuously evolving and … the cytokine storm with an
emphasis on new cytokine blockades. We also go into the pathophysiology of the cytokine storm in …

… Figure 2 SARS-CoV-2 induces cytokine storm formation and increased levels of angiotensin
II. Such alterations contribute to the activation of the coagulation cascade and, consequently…

… significant evolution in the definition and management of sepsis over the last three decades.
This is driven in part due to the advances made in our understanding of its pathophysiology. …