Mouse kidney development

AJ Davidson - African Scientist, 2019 - ojs.klobexjournals.com
regulatory molecules must limit the action of Wnt9b. One such factor is Six2, which is
expressed by the cap mesenchyme and functions to suppress the ectopic formation of pre-tubular …

[HTML][HTML] The function of miRNAs in the process of kidney development

P Sun, J Wang, T Ilyasova, A Shumadalova… - Non-coding RNA …, 2023 - Elsevier
… In recent years, there has been a growing interest in exploring the role of miRNAs as
essential regulatory molecules in kidney development and diseases. This field of study has …

Does renal repair recapitulate kidney development?

MH Little, P Kairath - Journal of the American Society of …, 2017 - journals.lww.com
… Over a decade ago, it was proposed that the regulation of tubular repair in the kidney might
… The molecular pathways expressed during normal kidney morphogenesis in the mouse, …

[HTML][HTML] Cellular and molecular mechanisms of kidney development: from the embryo to the kidney organoid

N Khoshdel Rad, N Aghdami… - Frontiers in cell and …, 2020 - frontiersin.org
… for pH and electrolyte regulation, and … of kidney organoids from hPSCs by assessing the
cells at each step of nephrogenesis has also expanded our knowledge of kidney development. …

[HTML][HTML] Current epigenetic insights in kidney development

K Chan, X Li - Genes, 2021 - mdpi.com
kidney development is also regulated by epigenetic mechanisms. This is essential for
proper development through the various stages of kidneymolecular mechanisms of kidney

Wnt signaling in kidney development and disease

Y Wang, CJ Zhou, Y Liu - Progress in molecular biology and translational …, 2018 - Elsevier
… after injury.6, 13 In this chapter, we provide a comprehensive review on the expression,
regulation, and function of Wnt/β-catenin signaling in the context of kidney development and …

[PDF][PDF] Dissecting the global dynamic molecular profiles of human fetal kidney development by single-cell RNA sequencing

P Wang, Y Chen, J Yong, Y Cui, R Wang, L Wen… - Cell reports, 2018 - cell.com
… Furthermore, we identified critical transcriptional regulators and signaling pathways … human
fetal kidneys remains limited. To address the key features of human fetal kidney development…

[HTML][HTML] The origins and functions of tissue-resident macrophages in kidney development

DAD Munro, J Hughes - Frontiers in physiology, 2017 - frontiersin.org
… Once in the kidney, tissue-specific transcriptional regulators … of kidney macrophages is
the result of kidney niches being … precursors throughout kidney development and phases of …

[HTML][HTML] Identification of candidate PAX2-regulated genes implicated in human kidney development

Y Yamamura, K Furuichi, Y Murakawa, S Hirabayashi… - Scientific reports, 2021 - nature.com
… This knowledge provides new clues for a deeper understanding of PAX2-associated
biology in humans, including the molecular pathogenesis of RCS, and mechanisms of human …

Cellular and molecular determinants of normal and abnormal kidney development

MS Tham, IM Smyth - Wiley Interdisciplinary Reviews …, 2019 - Wiley Online Library
… , much remains to be learned about how this process is regulated. In particular, the factors
which influence the decision of nephron progenitor cells in the CM to commit to nephron …