Historically, research into the lymphatic system has been overlooked due to both a lack of
knowledge and limited recognition of its importance. In the last decade however, lymphatic …

The secondary lymphatic valve is a bi-leaflet structure frequent throughout collecting vessels
that serves to prevent retrograde flow of lymph. Despite its vital function in lymph flow and …

The recent advances in our understanding of lymphatic physiology and the role of the
lymphatics in actively regulating fluid balance, lipid transport, and immune cell trafficking has …

The lymphatic system is vital to the circulatory and immune systems, performing a range of
important functions such as transport of interstitial fluid, fatty acid, and immune cells …

Initial lymphatic vessels are made up of overlapped endothelial cells that act as
unidirectional valves enabling one-way drainage of tissue fluid into the lumen of the initial …

Physical forces, including mechanical stretch, fluid pressure, and shear forces alter
lymphatic vessel contractions and lymph flow. Gravitational forces can affect these forces …

The lymphatic system comprises a series of elements, lymphangions, separated by valves
and possessed of active, contractile walls to pump interstitial fluid from its collection in the …

A primary purpose of the lymphatic system is to transport fluid from peripheral tissues to the
central venous system in order to maintain tissue–fluid balance. Failure to perform this task …

Abstract Background: Lymph nodes (LNs) are positioned strategically throughout the body
as critical mediators of lymph filtration and immune response. Lymph carries cytokines …

The lymphatic system is an open-ended network of vessels that run in parallel to the blood
circulation system. These vessels are present in almost all of the tissues of the body to …