Genomic landscape of CpG rich elements in human

VN Babenko, IV Chadaeva, YL Orlov - BMC evolutionary biology, 2017 - Springer
Abstract Background The studies on CpG islands (CGI) and Alu elements functions,
evolution, and distribution in the genome started since the discovery in nineteen eighties …

CpG islands: A historical perspective

F Antequera, A Bird - CpG Islands: Methods and Protocols, 2018 - Springer
The discovery of CpG islands (CGIs) and the study of their structure and properties run
parallel to the development of molecular biology in the last two decades of the twentieth …

Synthetic CpG islands reveal DNA sequence determinants of chromatin structure

E Wachter, T Quante, C Merusi, A Arczewska, F Stewart… - Elife, 2014 - elifesciences.org
The mammalian genome is punctuated by CpG islands (CGIs), which differ sharply from the
bulk genome by being rich in G+ C and the dinucleotide CpG. CGIs often include …

CpG_MI: a novel approach for identifying functional CpG islands in mammalian genomes

J Su, Y Zhang, J Lv, H Liu, X Tang, F Wang… - Nucleic acids …, 2010 - academic.oup.com
ABSTRACT CpG islands (CGIs) are CpG-rich regions compared to CpG-depleted bulk DNA
of mammalian genomes and are generally regarded as the epigenetic regulatory regions in …

CpG Island microarray probe sequences derived from a physical library are representative of CpG Islands annotated on the human genome

LE Heisler, D Torti, PC Boutros, J Watson… - Nucleic acids …, 2005 - academic.oup.com
An effective tool for the global analysis of both DNA methylation status and protein–
chromatin interactions is a microarray constructed with sequences containing regulatory …

CpG island density and its correlations with genomic features in mammalian genomes

L Han, B Su, WH Li, Z Zhao - Genome biology, 2008 - Springer
Background CpG islands, which are clusters of CpG dinucleotides in GC-rich regions, are
considered gene markers and represent an important feature of mammalian genomes …

CpG-island-based annotation and analysis of human housekeeping genes

L Zhang, Z Dai, J Yu, M Xiao - Briefings in bioinformatics, 2021 - academic.oup.com
By reviewing previous CpG-related studies, we consider that the transcription regulation of
about half of the human genes, mostly housekeeping (HK) genes, involves CpG islands …

Features and trend of loss of promoter-associated CpG islands in the human and mouse genomes

C Jiang, L Han, B Su, WH Li… - Molecular biology and …, 2007 - academic.oup.com
CpG islands (CGIs) are often considered as gene markers, but the number of CGIs varies
among mammalian genomes that have similar numbers of genes. In this study, we …

Identifying CpG islands by different computational techniques

B Hutter, M Paulsen, V Helms - OMICS A Journal of Integrative …, 2009 - liebertpub.com
CpG islands (CGIs) are generally regarded as important epigenetic regulatory elements due
to their association with promoter regions. However, identification of functional CGIs is …

Dualism of gene GC content and CpG pattern in regard to expression in the human genome: magnitude versus breadth

AE Vinogradov - Trends in Genetics, 2005 - cell.com
In this article, I show that, in the human genome, the GC content in genes (but not the CpG
island in the promoter) is related to the maximum level of gene expression among tissues …