How, when, and why do organisms, their tissues, and their cells age remain challenging
issues, although researchers have identified multiple mechanistic causes of aging, and …

Bats are the longest-lived mammals, given their body size. However, the underlying
molecular mechanisms of their extended healthspans are poorly understood. To address …

Aging, or senescence, has typically been measured by demographic analysis, which has its
merits but is blind to key aspects of functional development and deterioration. If one uses …

Bats are the longest-lived mammals given their body size with majority of species exhibiting
exceptional longevity. However, there are some short-lived species that do not exhibit …

Comparative analyses of bats indicate that hibernation is associated with increased
longevity among species. However, it is not yet known if hibernation affects biological …

Bats and birds live substantially longer on average than non-flying mammals of similar body
size. The combination of small body size, high metabolic rates, and long lifespan in bats and …

The steadily increasing number of elderly individuals in our societies imposes an increased
burden on our healthcare system due to an accompanying rise in chronic age-related …

Compared to chimpanzees (Pan troglodytes), the onset of aging appears to be delayed in
the human species. Herein, we studied human–chimpanzee orthologous gene pairs to …

Autophagy maintains cellular homeostasis and its dysfunction has been implicated in aging.
Bats are the longest-lived mammals for their size, but the molecular mechanisms underlying …

The challenges of surviving periods of increased physiological stress elicit selective
pressures that drive adaptations to overcome hardships. Bats in the Palearctic region …