Bats hold considerable potential for understanding exceptional longevity because some
species can live eight times longer than other mammals of similar size. Estimating their age …

Exceptionally long-lived species, including many bats, rarely show overt signs of aging,
making it difficult to determine why species differ in lifespan. Here, we use DNA methylation …

Comparative analyses of bats indicate that hibernation is associated with increased
longevity among species. However, it is not yet known if hibernation affects biological …

The age profile of populations fundamentally affects their conservation status. Yet, age is
frequently difficult to assess in wild animals. Here, we assessed the use of DNA methylation …

Bats are the longest-lived mammals, given their body size. However, the underlying
molecular mechanisms of their extended healthspans are poorly understood. To address …

DNA methylation profiles have been used to develop biomarkers of aging known as
epigenetic clocks, which predict chronological age with remarkable accuracy and show …

Across mammals, the epigenome is highly predictive of chronological age. These
“epigenetic clocks,” most of which have been built using DNA methylation (DNAm) profiles …

Age structure is a fundamental aspect of animal population biology. Age is strongly related
to individual physiological condition, reproductive potential and mortality rate. Currently …

DNA methylation (DNAm) is a key mechanism for regulating gene expression in animals
and levels are known to change with age. Recent studies have used DNAm changes as a …

ABSTRACT DNA methylation profiles have been used to develop biomarkers of aging
known as epigenetic clocks, which predict chronological age with remarkable accuracy and …