Target of rapamycin (TOR) is an evolutionarily conserved protein kinase that controls
multiple cellular processes upon various intracellular and extracellular stimuli. Since its first …

The target of rapamycin (TOR) is a serine/threonine kinase of the phosphatidylinositol
kinase-related kinase family and is highly conserved from yeast to mammals. TOR functions …

The target of rapamycin (TOR) is a conserved Ser/Thr kinase that regulates cell growth and
metabolism in response to environmental cues. Here, highlighting contributions from studies …

The target of rapamycin, TOR, is an essential ser/thr protein kinase that functions in two
distinct multiprotein complexes, TOR complex 1 and 2. The structure and functions of these …

Abstract The Target of Rapamycin (TOR) proteins function in signaling pathways that
promote protein synthesis and cell growth. In yeast, TOR signaling is regulated by nutrient …

The target of rapamycin (TOR) proteins in Saccharomyces cerevisiae, TOR1 and TOR2,
redundantly regulate growth in a rapamycin-sensitive manner. TOR2 additionally regulates …

The target of rapamycin (TOR) is an evolutionarily conserved protein kinase that regulates
cell growth in response to various environmental as well as intracellular cues through the …

Background The TOR (target of rapamycin) ser/thr protein kinase is the central component of
a eukaryotic signaling pathway that regulates growth and is the direct target of the clinically …

Research on TOR has grown exponentially during the last decade, generating a complex
model of the TOR signaling network. Rapamycin treatment provides a simple and …

Cell growth (increase in cell mass or size) is tightly coupled to nutrient availability, growth
factors and the energy status of the cell. The target of rapamycin (TOR) integrates all three …