A Hernandez-Segura, J Nehme, M Demaria - Trends in cell biology, 2018 - cell.com
Cellular senescence is a permanent state of cell cycle arrest that promotes tissue remodeling during development and after injury, but can also contribute to the decline of the …
BG Childs, M Durik, DJ Baker, JM Van Deursen - Nature medicine, 2015 - nature.com
Cellular senescence, a process that imposes permanent proliferative arrest on cells in response to various stressors, has emerged as a potentially important contributor to aging …
Cellular senescence is a state of irreversibly arrested proliferation, often induced by genotoxic stress [1]. Senescent cells participate in a variety of physiological and pathological …
N Kudlova, JB De Sanctis, M Hajduch - International Journal of Molecular …, 2022 - mdpi.com
Cellular senescence is defined as irreversible cell cycle arrest caused by various processes that render viable cells non-functional, hampering normal tissue homeostasis. It has many …
M Paez‐Ribes, E González‐Gualda… - EMBO molecular …, 2019 - embopress.org
Organismal ageing is a complex process driving progressive impairment of functionality and regenerative potential of tissues. Cellular senescence is a state of stable cell cycle arrest …
D Paramos-de-Carvalho, A Jacinto, L Saúde - Elife, 2021 - elifesciences.org
Cellular senescence is a highly complex and programmed cellular state with diverse and, at times, conflicting physiological and pathological roles across the lifespan of an organism …
F Jochems, B Thijssen, G De Conti, R Jansen… - Cell reports, 2021 - cell.com
Cellular senescence is characterized as a stable proliferation arrest that can be triggered by multiple stresses. Most knowledge about senescent cells is obtained from studies in primary …
Cellular senescence is a hallmark of aging defined by stable exit from the cell cycle in response to cellular damage and stress. Senescent cells (SnCs) can develop a …