A review of molecular mechanisms involved in anticancer and antiangiogenic effects of natural polyphenolic compounds

H Abbaszadeh, B Keikhaei… - Phytotherapy Research, 2019 - Wiley Online Library
The aim of this review is to obtain a further understanding of the reported inhibitory effects of
polyphenols on cancer cell proliferation and angiogenesis process and the probable …

[HTML][HTML] Functions of polyphenols and its anticancer properties in biomedical research: a narrative review

PB Bhosale, SE Ha, P Vetrivel, HH Kim… - Translational cancer …, 2020 - ncbi.nlm.nih.gov
Cancer is a major health concern as the incidence is growing worldwide and still lacks
successful therapies. Plant-derived functional foods are getting considerable attention …

Natural products against cancer angiogenesis

EB Khalid, ELMELK Ayman, H Rahman, G Abdelkarim… - Tumor Biology, 2016 - Springer
The process of angiogenesis is quite well-known nowadays. Some medicines and extracts
affecting this process are already used routinely in supporting the conventional treatment of …

In Vitro and in Vivo Antitumoral Effects of Combinations of Polyphenols, or Polyphenols and Anticancer Drugs: Perspectives on Cancer Treatment

M Fantini, M Benvenuto, L Masuelli, GV Frajese… - International journal of …, 2015 - mdpi.com
Carcinogenesis is a multistep process triggered by genetic alterations that activate different
signal transduction pathways and cause the progressive transformation of a normal cell into …

Recent updates on anticancer mechanisms of polyphenols

E Sharma, DC Attri, P Sati, P Dhyani… - Frontiers in Cell and …, 2022 - frontiersin.org
In today's scenario, when cancer cases are increasing rapidly, anticancer herbal
compounds become imperative. Studies on the molecular mechanisms of action of …

The role of polyphenol (flavonoids) compounds in the treatment of cancer cells

A Hazafa, KU Rehman, N Jahan, Z Jabeen - Nutrition and cancer, 2020 - Taylor & Francis
Cancer remains a second leading cause of deaths and major public health problem. It
occurs due to extensive DNA damage caused by ultraviolet radiations, ionizing radiations …

Anticancer efficacy of polyphenols and their combinations

A Niedzwiecki, MW Roomi, T Kalinovsky, M Rath - Nutrients, 2016 - mdpi.com
Polyphenols, found abundantly in plants, display many anticarcinogenic properties including
their inhibitory effects on cancer cell proliferation, tumor growth, angiogenesis, metastasis …

Dietary polyphenols in chemoprevention and synergistic effect in cancer: Clinical evidences and molecular mechanisms of action

S Patra, B Pradhan, R Nayak, C Behera, S Das… - Phytomedicine, 2021 - Elsevier
Background Epidemiological studies has revealed that a diet rich in fruits and vegetables
could lower the risk of certain cancers. In this setting, natural polyphenols are potent …

Cancer phytotherapy: Recent views on the role of antioxidant and angiogenesis activities

M Bahmani, H Shirzad, N Shahinfard… - Journal of evidence …, 2017 - journals.sagepub.com
Nowadays, increases in resistance of tumors to the current therapeutic agents have become
a problematic issue. Therefore, efforts to discover new anticancer compounds with high …

Antiangiogenic effects of flavonoids and chalcones

J Mojzis, L Varinska, G Mojzisova, I Kostova… - Pharmacological …, 2008 - Elsevier
Angiogenesis, the development of new blood vessels from the existing vasculature, is
essential in normal developmental processes. Uncontrolled angiogenesis is a major …