Research progress of matrine's anticancer activity and its molecular mechanism

F Chen, Y Pan, J Xu, B Liu, H Song - Journal of Ethnopharmacology, 2022 - Elsevier
Background and ethnopharmacological relevance: Matrine (MT), a type of alkaloid extracted
from the Sophora family of traditional Chinese medicine, has been documented to exert a …

Matrine: a promising natural product with various pharmacological activities

H Zhang, L Chen, X Sun, Q Yang, L Wan… - Frontiers in …, 2020 - frontiersin.org
Matrine is an alkaloid isolated from the traditional Chinese medicine Sophora flavescens
Aiton. At present, a large number of studies have proved that matrine has an anticancer …

Matrine exerts pharmacological effects through multiple signaling pathways: a comprehensive review

Y Lin, F He, L Wu, Y Xu, Q Du - Drug Design, Development and …, 2022 - Taylor & Francis
As The main effective monomer of the traditional Chinese medicine Sophora flavescens Ait,
matrine has a broad scope of pharmacological activities such as anti-tumor, anti …

Anti-tumor activities of matrine and oxymatrine: literature review

Y Liu, Y Xu, W Ji, X Li, B Sun, Q Gao, C Su - Tumor Biology, 2014 - Springer
Matrine (MT) and oxymatrine (OMT), two kinds of alkaloid components found in the roots of
Sophora species, have various pharmacological activities and are demonstrated to have …

A systematic review of the pharmacology, toxicology and pharmacokinetics of matrine

L You, C Yang, Y Du, W Wang, M Sun, J Liu… - Frontiers in …, 2020 - frontiersin.org
Matrine (MT) is a naturally occurring alkaloid and an bioactive component of Chinese herbs,
such as Sophora flavescens and Radix Sophorae tonkinensis. Emerging evidence suggests …

Research advances on anticancer activities of matrine and its derivatives: An updated overview

H ur Rashid, Y Xu, Y Muhammad, L Wang… - European journal of …, 2019 - Elsevier
Cancer is the second leading cause of mortality, only overcome by cardiovascular diseases,
and has caused more than 8.7 million deaths in 2015 all over the world. This figure is …

Chinese traditional medicine matrine: a review of its antitumor activities.

HW Cao, H Zhang, ZB Chen, ZJ Wu, YD Cui - 2011 - cabidigitallibrary.org
Matrine, a major component of the dried roots of Sophora flavescens Ait.(Leguminosae) has
a long history of use in traditional Chinese medicine. It has been found that matrine …

Anticancer effects of the Chinese medicine matrine on murine hepatocellular carcinoma cells

L Ma, S Wen, Y Zhan, Y He, X Liu, J Jiang - Planta medica, 2008 - thieme-connect.com
Matrine is a component of the traditional Chinese medical herb Sophora flavescens Ait,
which is widely used to treat diseases such as viral hepatitis, cardiac arrhythmia and skin …

Recent research progress of anti-tumor mechnism matrine

MJ Zhang, J Huang - Zhongguo Zhong yao za zhi= Zhongguo …, 2004 - europepmc.org
Matrine, as an active component of Chinese traditional medicine, has a great effect on anti-
inflammation, anti-arrhythmia and anti-fibrosis of liver cell. But the recent evidences indicate …

Matrine: Bioactivities and structural modifications

J Huang, H Xu - Current Topics in Medicinal Chemistry, 2016 - ingentaconnect.com
Matrine is a quinolizidine alkaloid isolated from the roots of Sophora flavescens (Kushen),
Sophora tonkinensis, and Sophora alopecuroides (Kudouzi). Matrine and its derivatives …