Kidneys are bilateral organs required to maintain homeostasis in the body through the
regulation of fluid composition and the excretion of metabolic waste products. The initial …

The mammalian kidney consists of highly specialised cells that function in an integrated
manner to maintain homeostasis of body fluids, electrolytes and nutrients. Formation of …

Organogenesis of the kidney has been intensely studied for over a century. In recent years
advances in molecular techniques have not only made great inroads into exploring the …

As in most organs, the emerging theme in kidney development is the importance of cross-
talk between several tissues and cell lineages to allow morphogenesis to proceed in a …

The mammalian kidney and lower urinary tract maintains and regulates water balance, acid–
base homeostasis, electrolyte equilibrium, and waste excretion. The performance of these …

The mammalian kidney is a vital organ with considerable cellular complexity and functional
diversity. Kidney development is notable for requiring distinct but coincident tubulogenic …

In the last few years, the “old” embryology of mammalian kidney has been revisited and
reinterpreted with new eyes, in the light of immunohistochemistry and molecular biology …

The kidney plays an integral role in filtering the blood—removing metabolic by-products from
the body and regulating blood pressure. This requires the establishment of large numbers of …

Abnormalities of kidney and urinary tract development are the most common cause of end-
stage kidney failure in childhood in the United States. Over the past 20 years, the advent of …

Although it is not easy to investigate the regulatory basis of developmental processes in
most mammalian tissues, the mouse kidney has several distinct advantages as a model …