Efficacy and safety of dapagliflozin in acute heart failure: Rationale and design of the DICTATE-AHF trial

ZL Cox, SP Collins, M Aaron, GA Hernandez… - American heart …, 2021 - Elsevier
Background Dapagliflozin, a sodium-glucose cotransporter-2 inhibitor, reduces
cardiovascular death and worsening heart failure in patients with chronic heart failure and …

Efficacy and safety of dapagliflozin in patients with acute heart failure

ZL Cox, SP Collins, GA Hernandez, AT McRae III… - Journal of the American …, 2024 - jacc.org
Background The primary goals during acute heart failure (AHF) hospitalization are
decongestion and guideline-directed medical therapy (GDMT) optimization. Unlike diuretics …

Dapagliflozin in patients recently hospitalized with heart failure and mildly reduced or preserved ejection fraction

JW Cunningham, M Vaduganathan, BL Claggett… - Journal of the American …, 2022 - jacc.org
Background Patients recently hospitalized for heart failure (HF) are at high risk for
rehospitalization and death. Objectives The purpose of this study was to investigate clinical …

Impact of dapagliflozin treatment on renal function and diuretics use in acute heart failure: a pilot study

K Charaya, D Shchekochikhin, D Andreev… - Open …, 2022 - openheart.bmj.com
Objective To determine the impact of sodium-dependent glucose type 2 cotransporter
inhibitors on the renal function in acute heart failure. Methods In a single-centre, controlled …

Time to clinical benefit of dapagliflozin in patients with heart failure with mildly reduced or preserved ejection fraction: a prespecified secondary analysis of the …

M Vaduganathan, BL Claggett, P Jhund… - JAMA …, 2022 - jamanetwork.com
Importance Dapagliflozin was recently shown to reduce cardiovascular death or worsening
heart failure (HF) events in patients with HF with mildly reduced or preserved ejection …

Effect of dapagliflozin on outpatient worsening of patients with heart failure and reduced ejection fraction: a prespecified analysis of DAPA-HF

KF Docherty, PS Jhund, I Anand, O Bengtsson… - Circulation, 2020 - Am Heart Assoc
Background: In the DAPA-HF trial (Dapagliflozin and Prevention of Adverse Outcomes in
Heart Failure), dapagliflozin, added to guideline-recommended therapies, reduced the risk …

Time to clinical benefit of dapagliflozin and significance of prior heart failure hospitalization in patients with heart failure with reduced ejection fraction

DD Berg, PS Jhund, KF Docherty, SA Murphy… - JAMA …, 2021 - jamanetwork.com
Importance Dapagliflozin has been shown to reduce the risk of cardiovascular death or
worsening heart failure (HF) in patients with chronic HF and reduced ejection fraction …

[HTML][HTML] Dapagliflozin in heart failure with mildly reduced or preserved ejection fraction

SD Solomon, JJV McMurray, B Claggett… - … England Journal of …, 2022 - Mass Medical Soc
Background Sodium–glucose cotransporter 2 (SGLT2) inhibitors reduce the risk of
hospitalization for heart failure and cardiovascular death among patients with chronic heart …

Dapagliflozin across the range of ejection fraction in patients with heart failure: a patient-level, pooled meta-analysis of DAPA-HF and DELIVER

PS Jhund, T Kondo, JH Butt, KF Docherty… - Nature medicine, 2022 - nature.com
Whether the sodium–glucose cotransporter 2 inhibitor dapagliflozin reduces the risk of a
range of morbidity and mortality outcomes in patients with heart failure regardless of ejection …

Efficacy and safety of dapagliflozin in patients with type 2 diabetes and concomitant heart failure

M Kosiborod, I Gause-Nilsson, J Xu… - Journal of diabetes and …, 2017 - Elsevier
Aim We investigated the efficacy and safety of dapagliflozin, a sodium–glucose
cotransporter 2 inhibitor, in patients with type 2 diabetes mellitus (T2DM) and heart failure …