Of microbes and minds: a narrative review on the second brain aging

R Calvani, A Picca, MR Lo Monaco, F Landi… - Frontiers in …, 2018 - frontiersin.org
In recent years, an extensive body of literature focused on the gut–brain axis and the
possible role played by the gut microbiota in modulating brain morphology and function from …

The gut microbiota is an emerging target for improving brain health during ageing

M Boehme, KE Guzzetta, C Wasén, LM Cox - Gut microbiome, 2023 - cambridge.org
The gut microbiota plays crucial roles in maintaining the health and homeostasis of its host
throughout lifespan, including through its ability to impact brain function and regulate …

Gut microbiota interact with the brain through systemic chronic inflammation: implications on neuroinflammation, neurodegeneration, and aging

Y Mou, Y Du, L Zhou, J Yue, X Hu, Y Liu… - Frontiers in …, 2022 - frontiersin.org
It has been noticed in recent years that the unfavorable effects of the gut microbiota could
exhaust host vigor and life, yet knowledge and theory are just beginning to be established …

Gut microbiota: critical controller and intervention target in brain aging and cognitive impairment

H Li, J Ni, H Qing - Frontiers in aging neuroscience, 2021 - frontiersin.org
The current trend for the rapid growth of the global aging population poses substantial
challenges for society. The human aging process has been demonstrated to be closely …

Gut instincts: microbiota as a key regulator of brain development, ageing and neurodegeneration

TG Dinan, JF Cryan - The Journal of physiology, 2017 - Wiley Online Library
There is a growing realisation that the gut–brain axis and its regulation by the microbiota
may play a key role in the biological and physiological basis of neurodevelopmental, age …

The influence of gut microbiota alteration on age-related neuroinflammation and cognitive decline

AS Alsegiani, ZA Shah - Neural Regeneration Research, 2022 - journals.lww.com
Recent emerging research on intestinal microbiota and its contribution to the central nervous
system during health and disease has attracted significant attention. Age-related intestinal …

Gut and brain: investigating physiological and pathological interactions between microbiota and brain to gain new therapeutic avenues for brain diseases

G Deidda, M Biazzo - Frontiers in Neuroscience, 2021 - frontiersin.org
Brain physiological functions or pathological dysfunctions do surely depend on the activity of
both neuronal and non-neuronal populations. Nevertheless, over the last decades …

Effects of gut microbiota on neurodegenerative diseases

S Khatoon, N Kalam, S Rashid, G Bano - Frontiers in Aging …, 2023 - frontiersin.org
A progressive degradation of the brain's structure and function, which results in a reduction
in cognitive and motor skills, characterizes neurodegenerative diseases (NDs) such as …

A review of the preclinical and clinical studies on the role of the gut microbiome in aging and neurodegenerative diseases and its modulation

HM Hashim, S Makpol - Frontiers in cellular neuroscience, 2022 - frontiersin.org
As the world population ages, the burden of age-related health problems grows, creating a
greater demand for new novel interventions for healthy aging. Advancing aging is related to …

The contribution of age-related changes in the gut-brain axis to neurological disorders

R Khan, CM Di Gesù, J Lee, LD McCullough - Gut microbes, 2024 - Taylor & Francis
Trillions of microbes live symbiotically in the host, specifically in mucosal tissues such as the
gut. Recent advances in metagenomics and metabolomics have revealed that the gut …