Vascular dementia (VaD) is a leading cause of dementia in the elderly together with
Alzheimer's disease with limited treatment options. Poor understanding of the …

Aging influences the pathogenesis and progression of several major diseases affecting both
the cardiovascular system (CVS) and central nervous system (CNS). Defining the common …

Cerebrovascular disease (CVD) is the second most common cause of cognitive impairment
and dementia in aged population. CVD presents in a myriad number of clinical ways based …

Among omics, the proteomics assumes a unique role in that it offers the effectors or
actuators of a biological condition. This brief review attempts to summarize the development …

Brain small vessel disease (SVD) refers to a variety of structural and functional changes
affecting small arteries and micro vessels, and manifesting as white matter changes …

Atherosclerosis is a chronic inflammatory disease with complex pathobiology and one of the
most common causes of cardiovascular events. The process is characterized by complex …

Introduction: Inflammation is integral in the neuropathology of both chronic and acute
neurological disorders. Knowing the inflammatory profile is important for clarification of …

Cerebral amyloid angiopathy (CAA) is a form of small vessel disease characterised by the
progressive deposition of amyloid β protein in the cerebral vasculature, inducing symptoms …

Aging is a major risk factor for cerebrovascular disease; however, the molecular
mechanisms of cerebrovascular aging remain to be clarified. The aim of this study was to …

Decades of research has stunned us with the very distinctive anatomy and physiology of our
brain, and on the other hand, its complexity has always posed great difficulty in treating its …