Nucleoporins (nups) in the central channel of nuclear pore complexes (NPCs) form a
selective barrier that suppresses the diffusion of most macromolecules while enabling rapid …

Delivering the virus genome into the host nucleus through the nuclear pore complex (NPC)
is pivotal in human immunodeficiency virus 1 (HIV-1) infection. The mechanism of this …

Nuclear pore complexes (NPCs) form gateways that control molecular exchange between
the nucleus and the cytoplasm. They impose a diffusion barrier to macromolecules and …

The nuclear pore complex (NPC) is a huge protein system spanning the nuclear envelope
whose central pore (with diameters> 40 nm) is filled with intrinsically disordered proteins (FG …

DNA nanotechnology provides a versatile and powerful tool to dissect the structure–function
relationship of biomolecular machines like the nuclear pore complex (NPC), an enormous …

Nuclear pore complexes regulate the selective exchange of RNA and proteins across the
nuclear envelope in eukaryotic cells. Biomimetic strategies offer new opportunities to …

The capsid of human immunodeficiency virus 1 (HIV-1) plays a pivotal role in viral nuclear
import, but the mechanism by which the viral core passages the nuclear pore complex …

Nuclear pore complexes (NPCs) mediate nucleocytoplasmic transport of specific
macromolecules while impeding the exchange of unsolicited material. However, key aspects …

Abstract Nuclear Pore Complexes (NPCs) regulate bidirectional transport between the
nucleus and the cytoplasm. Intrinsically disordered FG-Nups line the NPC lumen and form a …

Nuclear pore complexes (NPCs) are highly selective gates that mediate the exchange of all
proteins and nucleic acids between the cytoplasm and the nucleus. Their selectivity relies on …