Early life stress, air pollution, inflammation, and disease: an integrative review and immunologic model of social-environmental adversity and lifespan health

HAO Alvarez, LD Kubzansky, MJ Campen… - Neuroscience & …, 2018 - Elsevier
Socially disadvantaged individuals are at greater risk for simultaneously being exposed to
adverse social and environmental conditions. Although the mechanisms underlying joint …

An integrated socio-environmental model of health and well-being: a conceptual framework exploring the joint contribution of environmental and social exposures to …

HA Olvera Alvarez, AA Appleton, CH Fuller… - Current environmental …, 2018 - Springer
Purpose of the review Environmental and social determinants of health often co-occur,
particularly among socially disadvantaged populations, yet because they are usually studied …

Stressful early life experiences and immune dysregulation across the lifespan

CP Fagundes, R Glaser, JK Kiecolt-Glaser - Brain, behavior, and immunity, 2013 - Elsevier
There is considerable evidence that stressful early life events influence a variety of physical
health problems later in life. Childhood adversity has been linked to elevated rates of …

Mechanisms linking early life stress to adult health outcomes

SE Taylor - Proceedings of the National Academy of …, 2010 - National Acad Sciences
Research relating stress to health has progressed from anecdotal evidence in the 1930s
and 1940s to complex multivariate models that identify underlying longitudinal mechanisms …

Environmental health disparities: a framework integrating psychosocial and environmental concepts

GC Gee, DC Payne-Sturges - Environmental health perspectives, 2004 - ehp.niehs.nih.gov
Although it is often acknowledged that social and environmental factors interact to produce
racial and ethnic environmental health disparities, it is still unclear how this occurs. Despite …

[PDF][PDF] Biological pathways linking social conditions and health

LD Kubzansky, TE Seeman, MM Glymour - Social epidemiology, 2014 - ndl.ethernet.edu.et
This chapter considers mechanisms that may explain how social exposures “outside the
body” get under the skin to influence physical health and disease. We conceptualize the …

From the outside in: biological mechanisms linking social and environmental exposures to chronic disease and to health disparities

SP Bagby, D Martin, ST Chung… - American journal of …, 2019 - ajph.aphapublications.org
The ongoing epidemic of chronic diseases involves a spectrum of clinical entities now
understood to represent late manifestations of progressive metabolic dysfunction initiated in …

[HTML][HTML] Immune and epigenetic pathways linking childhood adversity and health across the lifespan

MA Chen, AS LeRoy, M Majd, JY Chen… - Frontiers in …, 2021 - frontiersin.org
Childhood adversity is associated with a host of mental and physical health problems across
the lifespan. Individuals who have experienced childhood adversity (eg, child abuse and …

[HTML][HTML] Air pollution, stress, and allostatic load: linking systemic and central nervous system impacts

EM Thomson - Journal of Alzheimer's Disease, 2019 - content.iospress.com
Air pollution is a risk factor for cardiovascular and respiratory morbidity and mortality. A
growing literature also links exposure to diverse air pollutants (eg, nanoparticles, particulate …

Stress and chronic illness: The inflammatory pathway

RL Acabchuk, J Kamath, JD Salamone… - Social Science & …, 2017 - Elsevier
A recent study published in Social Science & Medicine provides a compelling example of
how psychoneuroimmunology and epigenetics are being utilized in the field of health …