Utilising artificial intelligence to determine patients at risk of a rare disease: idiopathic pulmonary arterial hypertension

DG Kiely, O Doyle, E Drage, H Jenner… - Pulmonary …, 2019 - journals.sagepub.com
Idiopathic pulmonary arterial hypertension is a rare and life-shortening condition often
diagnosed at an advanced stage. Despite increased awareness, the delay to diagnosis …

High levels of healthcare utilization prior to diagnosis in idiopathic pulmonary arterial hypertension support the feasibility of an early diagnosis algorithm: the SPHInX …

R Bergemann, J Allsopp, H Jenner… - Pulmonary …, 2018 - journals.sagepub.com
Idiopathic pulmonary arterial hypertension (iPAH) is a rare progressive, life-shortening
disease, usually diagnosed at an advanced stage. We hypothesize that patients with iPAH …

A claims‐based, machine‐learning algorithm to identify patients with pulmonary arterial hypertension

B Hyde, CJ Paoli, S Panjabi… - Pulmonary …, 2023 - Wiley Online Library
Many patients with pulmonary arterial hypertension (PAH) experience substantial delays in
diagnosis, which is associated with worse outcomes and higher costs. Tools for diagnosing …

Accuracy of algorithms to identify pulmonary arterial hypertension in administrative data: a systematic review

KR Gillmeyer, MM Lee, AP Link, ES Klings, ST Rinne… - Chest, 2019 - Elsevier
Background The diagnosis of pulmonary arterial hypertension (PAH) is challenging, and
there is significant overlap with the more heterogenous diagnosis of pulmonary …

Claims‐based algorithms for identifying patients with pulmonary hypertension: a comparison of decision rules and machine‐learning approaches

MS Ong, JG Klann, KJ Lin, BA Maron… - Journal of the …, 2020 - Am Heart Assoc
Background Real‐world healthcare data are an important resource for epidemiologic
research. However, accurate identification of patient cohorts—a crucial first step …

Screening strategies for pulmonary arterial hypertension

DG Kiely, A Lawrie, M Humbert - European Heart Journal …, 2019 - academic.oup.com
Pulmonary arterial hypertension (PAH) is rare and, if untreated, has a median survival of 2–3
years. Pulmonary arterial hypertension may be idiopathic (IPAH) but is frequently associated …

An algorithm to identify cases of pulmonary arterial hypertension from the electronic medical record

KP Schuler, AR Hemnes, J Annis, E Farber-Eger… - Respiratory …, 2022 - Springer
Background Study of pulmonary arterial hypertension (PAH) in claims-based (CB) cohorts
may facilitate understanding of disease epidemiology, however previous CB algorithms to …

Artificial intelligence for early prediction of pulmonary hypertension using electrocardiography

J Kwon, KH Kim, J Medina-Inojosa, KH Jeon… - The Journal of Heart and …, 2020 - Elsevier
BACKGROUND Screening and early diagnosis of pulmonary hypertension (PH) are critical
for managing progression and preventing associated mortality; however, there are no tools …

Identifying patients with pulmonary arterial hypertension using administrative claims algorithms

SC Mathai, AR Hemnes, S Manaker… - Annals of the …, 2019 - atsjournals.org
Retrospective administrative claims database studies provide real-world evidence about
treatment patterns, healthcare resource use, and costs for patients and are increasingly …

Validation of claims-based algorithms for pulmonary arterial hypertension

R Papani, G Sharma, A Agarwal… - Pulmonary …, 2018 - journals.sagepub.com
Administrative claims studies do not adequately distinguish pulmonary arterial hypertension
(PAH) from other forms of pulmonary hypertension (PH). Our aim is to develop and validate …