Schizophrenia is a genetically and clinically heterogeneous disorder. Genetic risk factors for the disorder may differ between the sexes or between multiply affected families compared to …
Epidemiologists and geneticists have tended to explore their respective domains independently, and as a consequence, these fields have drifted apart. The aim of this article …
We have performed a genome-wide association study (GWAS) of schizophrenia in a Norwegian discovery sample of 201 cases and 305 controls (TOP study) with a focused …
Recent molecular studies have implicated common alleles of small to moderate effect and rare alleles with larger effect sizes in the genetic architecture of schizophrenia (SCZ). It is …
Schizophrenia is a highly heritable disorder. Genetic risk is conferred by a large number of alleles, including common alleles of small effect that might be detected by genome-wide …
B Lerer, RH Segman, A Hamdan, K Kanyas… - Molecular …, 2003 - nature.com
Schizophrenia is a complex neuropsychiatric disorder to which an as-yet-unknown number of genes contribute, interacting with each other and the environment. Linkage analyses have …
R Van Winkel, G Esquivel, G Kenis… - CNS neuroscience & …, 2010 - Wiley Online Library
The recent advent of genome‐wide mass‐marker technology has resulted in renewed optimism to unravel the genetic architecture of psychotic disorders. Genome‐wide …
Genetic association studies on schizophrenia (SZ) have been repeatedly performed over the last two decades, resulting in a consensus that results are generally inconsistent. This …
Prior family and adoption studies have suggested a genetic relationship between schizophrenia and schizotypy. However, this has never been verified using linkage …