CADASIL brain vessels show a HTRA1 loss-of-function profile

A Zellner, E Scharrer, T Arzberger, C Oka… - Acta …, 2018 - Springer
Cerebral autosomal dominant arteriopathy with subcortical infarcts and
leukoencephalopathy (CADASIL) and a phenotypically similar recessive condition …

The pathogenesis of CADASIL: an update

RN Kalaria, M Viitanen, H Kalimo, M Dichgans… - Journal of the …, 2004 - Elsevier
Cerebral autosomal dominant arteriopathy with subcortical infarcts and
leukoencephalopathy (CADASIL) appears to be the most common form of hereditary stroke …

Clinical and genetic aspects of CADASIL

T Mizuno, I Mizuta, A Watanabe-Hosomi… - Frontiers in aging …, 2020 - frontiersin.org
Cerebral autosomal dominant arteriopathy with subcortical infarcts and
leukoencephalopathy (CADASIL), a hereditary cerebral small vessel disease caused by …

Notch3 Arg170Cys knock-in mice display pathologic and clinical features of the neurovascular disorder cerebral autosomal dominant arteriopathy with subcortical …

G Wallays, D Nuyens, R Silasi-Mansat… - … , and vascular biology, 2011 - Am Heart Assoc
Objective—Cerebral autosomal dominant arteriopathy with subcortical infarcts and
leukoencephalopathy (CADASIL) is an adult-onset neurovascular disorder caused by …

CADASIL: experimental insights from animal models

C Ayata - Stroke, 2010 - Am Heart Assoc
Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and
Leukoencephalopathy (CADASIL) syndrome is the most common monogenic inherited form …

[HTML][HTML] CADASIL: a NOTCH3-associated cerebral small vessel disease

L Yuan, X Chen, J Jankovic, H Deng - Journal of Advanced Research, 2024 - Elsevier
Background Cerebral autosomal dominant arteriopathy with subcortical infarcts and
leukoencephalopathy (CADASIL) is the most common hereditary cerebral small vessel …

Pathophysiological mechanisms and potential therapeutic targets in cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy …

M Locatelli, A Padovani, A Pezzini - Frontiers in pharmacology, 2020 - frontiersin.org
Cerebral autosomal dominant arteriopathy with subcortical infarcts and
leukoencephalopathy (CADASIL), is a hereditary small-vessels angiopathy caused by …

[HTML][HTML] Update on the epidemiology, pathogenesis, and biomarkers of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy

Y Yamamoto, YC Liao, YC Lee, M Ihara… - Journal of Clinical …, 2023 - ncbi.nlm.nih.gov
Cerebral autosomal dominant arteriopathy with subcortical infarcts and
leukoencephalopathy (CADASIL) is the most common monogenic disorder of the cerebral …

CADASIL: yesterday, today, tomorrow

H Chabriat, A Joutel… - European journal of …, 2020 - Wiley Online Library
Background and purpose In 2019, the Brain Prize crowned the discovery of CADASIL in the
1990s and research efforts on this archetypal small vessel disease of the brain over 40 …

[HTML][HTML] Blood biomarkers in a mouse model of CADASIL

V Primo, M Graham, AA Bigger-Allen, JM Chick… - Brain Research, 2016 - Elsevier
Mutations in NOTCH 3 are the cause of cerebral autosomal dominant arteriopathy with
subcortical infarcts and leukoencephalopathy (CADASIL), a neurological disorder …