Autoinflammatory diseases and cytokine storms—imbalances of innate and adaptative immunity

A Marcuzzi, E Melloni, G Zauli, A Romani… - International Journal of …, 2021 - mdpi.com
Innate and adaptive immune responses have a well-known link and represent the distinctive
origins of several diseases, many of which may be the consequence of the loss of balance …

COVID-19 immunobiology: lessons learned, new questions arise

A Kaklamanos, K Belogiannis, P Skendros… - Frontiers in …, 2021 - frontiersin.org
There is strong evidence that COVID-19 pathophysiology is mainly driven by a
spatiotemporal immune deregulation. Both its phenotypic heterogeneity, spanning from …

Cytokine storm and COVID-19: a chronicle of pro-inflammatory cytokines

A Fara, Z Mitrev, RA Rosalia, BM Assas - Open biology, 2020 - royalsocietypublishing.org
Coronavirus disease 2019 (COVID-19) has swept the world, unlike any other pandemic in
the last 50 years. Our understanding of the disease has evolved rapidly since the outbreak; …

Multisystem inflammatory syndrome and autoimmune diseases following COVID-19: molecular mechanisms and therapeutic opportunities

P Hosseini, MS Fallahi, G Erabi, M Pakdin… - Frontiers in molecular …, 2022 - frontiersin.org
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome-
coronavirus 2 (SARS-CoV-2), has led to huge concern worldwide. Some SARS-CoV-2 …

Immune response in COVID-19: addressing a pharmacological challenge by targeting pathways triggered by SARS-CoV-2

M Catanzaro, F Fagiani, M Racchi, E Corsini… - Signal transduction and …, 2020 - nature.com
To date, no vaccines or effective drugs have been approved to prevent or treat COVID-19
and the current standard care relies on supportive treatments. Therefore, based on the fast …

Regulation of inflammatory reaction in health and disease

M Fioranelli, MG Roccia, D Flavin, L Cota - International journal of …, 2021 - mdpi.com
Inflammation is a key mechanism for the clearance of infective agents and other
inflammatory triggers and is pivotal for the repairing processes of the affected tissues …

COVID 19: a clue from innate immunity

D Birra, M Benucci, L Landolfi, A Merchionda, G Loi… - Immunologic …, 2020 - Springer
The recent COVID-19 pandemic has had a significant impact on our lives and has rapidly
expanded to reach more than 4 million cases worldwide by May 2020. These cases are …

Lessons learned to date on COVID-19 hyperinflammatory syndrome: considerations for interventions to mitigate SARS-CoV-2 viral infection and detrimental …

M Cardone, M Yano, AS Rosenberg… - Frontiers in …, 2020 - frontiersin.org
The first case of human transmission of SARS-CoV-2 was reported in China in December
2019. A few months later, this viral infection had spread worldwide and became a pandemic …

How do inflammatory mediators, immune response and air pollution contribute to COVID-19 disease severity? A lesson to learn

C Signorini, P Pignatti, T Coccini - Life, 2021 - mdpi.com
Inflammatory and immune processes are defensive mechanisms that aim to remove harmful
agents. As a response to infections, inflammation and immune response contribute to the …

[HTML][HTML] COVID-19 a triggering factor of autoimmune and multi-inflammatory diseases

EK Sher, A Ćosović, A Džidić-Krivić, EK Farhat, E Pinjić… - Life sciences, 2023 - Elsevier
SARS-Cov-2 virus has attracted a lot of attention globally, due to the autoimmune and
inflammatory processes that were observed during the development of Covid-19 disease …