Genome-wide association studies in schizophrenia: Recent advances, challenges and future perspective
Genome-wide association studies (GWAS) have proved to be a powerful approach for gene
discovery in schizophrenia; their findings have important implications not just for our …
discovery in schizophrenia; their findings have important implications not just for our …
Genome-wide association studies of schizophrenia: does bigger lead to better results?
SE Bergen, TL Petryshen - Current opinion in psychiatry, 2012 - journals.lww.com
Identifying the genetic underpinnings of complex diseases offers insight into the etiological
mechanisms leading to manifestation of the disease. New and more effective treatments for …
mechanisms leading to manifestation of the disease. New and more effective treatments for …
The emerging spectrum of allelic variation in schizophrenia: current evidence and strategies for the identification and functional characterization of common and rare …
BJ Mowry, J Gratten - Molecular psychiatry, 2013 - nature.com
After decades of halting progress, recent large genome-wide association studies (GWAS)
are finally shining light on the genetic architecture of schizophrenia. The picture emerging is …
are finally shining light on the genetic architecture of schizophrenia. The picture emerging is …
Genome-wide association analysis identifies 30 new susceptibility loci for schizophrenia
We conducted a genome-wide association study (GWAS) with replication in 36,180 Chinese
individuals and performed further transancestry meta-analyses with data from the Psychiatry …
individuals and performed further transancestry meta-analyses with data from the Psychiatry …
Integrated post-GWAS analysis sheds new light on the disease mechanisms of schizophrenia
Schizophrenia is a severe mental disorder with a large genetic component. Recent genome-
wide association studies (GWAS) have identified many schizophrenia-associated common …
wide association studies (GWAS) have identified many schizophrenia-associated common …
Genetics of schizophrenia: ready to translate?
Abstract Purpose of Review This is an era where we have significantly advanced the
understanding of the genetic architecture of schizophrenia. In this review, we consider how …
understanding of the genetic architecture of schizophrenia. In this review, we consider how …
Common variants conferring risk of schizophrenia: a pathway analysis of GWAS data
Unlike the typical analysis of single markers in genome-wide association studies (GWAS),
we incorporated Gene Set Enrichment Analysis (GSEA) and hypergeometric test and …
we incorporated Gene Set Enrichment Analysis (GSEA) and hypergeometric test and …
Genome-wide association study of schizophrenia in Japanese population
K Yamada, Y Iwayama, E Hattori, K Iwamoto, T Toyota… - PloS one, 2011 - journals.plos.org
Schizophrenia is a devastating neuropsychiatric disorder with genetically complex traits.
Genetic variants should explain a considerable portion of the risk for schizophrenia, and …
Genetic variants should explain a considerable portion of the risk for schizophrenia, and …
What next in schizophrenia genetics for the psychiatric genomics consortium?
A Corvin, PF Sullivan - Schizophrenia bulletin, 2016 - academic.oup.com
Over the last 8 years the Psychiatric Genomics Consortium (PGC; http://pgc. unc. edu) has
fundamentally changed the landscape for psychiatric genetics research. This has been …
fundamentally changed the landscape for psychiatric genetics research. This has been …
Comparative genetic architectures of schizophrenia in East Asian and European populations
Schizophrenia is a debilitating psychiatric disorder with approximately 1% lifetime risk
globally. Large-scale schizophrenia genetic studies have reported primarily on European …
globally. Large-scale schizophrenia genetic studies have reported primarily on European …