W Löscher, A Friedman - International journal of molecular sciences, 2020 - mdpi.com
… The blood–brainbarrier (BBB) is a dynamic and complex barrier essential for the normal function of the central nervous system (CNS). The existence of a physical interface between the …
G Bar-Klein, S Lublinsky, L Kamintsky, I Noyman… - Brain, 2017 - academic.oup.com
… blood–brainbarrierdysfunction and neuroinflammation. … anti-epileptogenic interventions were used; isoflurane anaesthesia and losartan. Our results show that early blood–brainbarrier …
AB Santos, A Carona, M Ettcheto, A Camins… - Acta Pharmacologica …, 2024 - nature.com
… vascular function and … roles in cerebrovascular dysfunction and epileptogenesis. This review critically discusses the purpose of KLFs in epileptogenic mechanisms and BBB dysfunction, …
F Meng, L Yao - Acta Epileptologica, 2020 - Springer
… excitation as well as blood-brainbarrier (BBB) dysfunction, and finally trigger the … roles of inflammatory mediators, including inflammatory cytokines, cells, and BBB, in epileptogenesis …
H Han, A Mann, D Ekstein, S Eyal - The AAPS journal, 2017 - Springer
… , similarly to studies of other braindisorders. An additional source … aimed at resecting the epileptogenicbrain tissue. Since … on the hippocampus, a main epileptogenic structure within the …
… epilepsy models show that brain inflammation can enhance … epileptogenesis could help to determine the role of inflammation in the progression of epilepsy and is of crucial importance …
… contributes to epileptogenesis, blood–brainbarrierdysfunction … We hypothesized that blood–brainbarrierdysfunction is temporally … role in the mediation of peri-ictal blood–brainbarrier …
JA Gorter, E Aronica, EA Van Vliet - Epilepsy currents, 2019 - journals.sagepub.com
… Research into the role of the blood–brainbarrier (BBB) in epilepsy … epileptogenicbrain tissue. At the same time it has become increasingly clear that (neuro)inflammation may play a role …
H Breuer, M Meier, S Schneefeld… - Journal of Cerebral …, 2017 - journals.sagepub.com
… Our findings will help to further evaluate the role of BBB impairment in epileptogenesis and provide a potential method to optimize timing of BBB protective treatment approaches. …