… Interleukin-1, an inflammatory cytokine, is considered to have diverse physiological … and
play an important role in health and disease. In this decade, interleukin-1 family members have …

… role for IL-1 in inflammatory atherogenesis is also predicted. To date, four potent inhibitors
of IL-1 are … , but also helped improve our understanding of the role of IL-1 in human disease. …

… -1 is now considered a key inducer of inflammation in PTL. This review will focus on the role
of IL-1 in PTL, and will discuss the efficacy of IL-1 receptor antagonists in the context of PTB. …

… In this review, we focus on the role of IL-1 in the pathogenesis of periodontal disease and
review the current understanding of the molecular mechanisms of IL-1 production and …

… production and activity of IL-1 in asthmatic patients and a functional role in animal models, but
also … regulators of increased IL-1 activity. This could inform pharmacogenomic studies of IL-…

Pulmonary artery smooth muscle cell (PA-SMC) proliferation and inflammation are key
components of pulmonary arterial hypertension (PAH). Interleukin (IL)-1β binds to IL-1 receptor (R…

… roles of IL-1 α and IL-β in initiating and sustaining the inflammatory processes, starting
from the unique biochemical and functional properties of these pleiotropic cytokines (Table 1). …

… of the two IL-1 isoforms and their correlation with skin diseases. This review discusses
the roles of IL-1α and IL-1β in skin diseases and the rationale for targeting the alpha isoform. …

Interleukin‐1 receptor accessory protein (IL‐1RAcP) is a member of the immunoglobulin
superfamily proteins consisting of soluble and membranous isoforms. IL‐1RAcP plays an …

… Single Ig IL-1- related receptors also appear to be involved in IL-1… In conclusion, IL-1 plays
an important role in a variety of … In conclusion, IL-1 family plays an important role in pulmonary …