Structure of SARS-CoV-2 spike protein

J Zhang, T Xiao, Y Cai, B Chen - Current opinion in virology, 2021 - Elsevier
… of the structure of the SARS-CoV-2 S protein and discuss the … of coronavirus S proteins,
including the full-length SARS-CoV… ID: 7KRR ), the stabilized soluble SARS-CoV-2 S trimer in the …

[HTML][HTML] Structural and functional analysis of the D614G SARS-CoV-2 spike protein variant

L Yurkovetskiy, X Wang, KE Pascal, C Tomkins-Tinch… - Cell, 2020 - cell.com
… The SARS-CoV-2 spike (S) protein variant D614G supplanted the ancestral virus
worldwide… D614G did not alter S protein synthesis, processing, or incorporation into SARS-CoV-2 …

Domains and functions of spike protein in Sars-Cov-2 in the context of vaccine design

X Xia - Viruses, 2021 - mdpi.com
SARS-CoV-2 uses its trimeric spike protein for binding to host angiotensin-converting … This
is a multi-step process involving three separate S protein cleavage events to prime the SARS-…

Human SARS CoV‐2 spike protein mutations

L Guruprasad - Proteins: Structure, Function, and Bioinformatics, 2021 - Wiley Online Library
… in 8155 proteins among 10333 human SARS-CoV-2 spike protein sequences analyzed in
… for all the spike proteins. The mutation sites are distributed over whole length of the protein

Prospect of SARS-CoV-2 spike protein: Potential role in vaccine and therapeutic development

SK Samrat, AM Tharappel, Z Li, H Li - Virus research, 2020 - Elsevier
… The most striking feature of the coronavirus is the club-shaped spike protein projecting from
… on the viral Spike protein have been found in circulating clinical SARS-CoV-2 strains (Korber …

Dynamics of the ACE2–SARS-CoV-2/SARS-CoV spike protein interface reveal unique mechanisms

A Ali, R Vijayan - Scientific reports, 2020 - nature.com
… of the spike (S) protein of SARS-CoV-2 and SARS-CoV bound to … Our results indicate that
SARS-CoV-2 and SARS-CoV … the residues of SARS-CoV-2 and SARS-CoV that consistently …

Composition and divergence of coronavirus spike proteins and host ACE2 receptors predict potential intermediate hosts of SARSCoV‐2

Z Liu, X Xiao, X Wei, J Li, J Yang, H Tan… - Journal of medical …, 2020 - Wiley Online Library
… It is noteworthy that SARS-CoV was the most widely distributed coronavirus in … SARS-CoV-2
reads and found that the spike protein sequence was present in pangolin SARS-like CoV (…

Potent binding of 2019 novel coronavirus spike protein by a SARS coronavirus-specific human monoclonal antibody

X Tian, C Li, A Huang, S Xia, S Lu, Z Shi… - Emerging microbes & …, 2020 - Taylor & Francis
… -nCoV and SARS-CoV, it is urgent to assess the cross-reactivity of anti-SARS CoV antibodies
with 2019-nCoV spike protein, … against 2019-nCoV. Here, we report for the first time that a …

A human antibody reveals a conserved site on beta-coronavirus spike proteins and confers protection against SARS-CoV-2 infection

P Zhou, M Yuan, G Song, N Beutler… - Science translational …, 2022 - science.org
CoV spike proteins for protective antibodies that may facilitate the development of pan–β-CoV
studies have shown that heterologous CoV spike protein immunizations in mice or mice …

Cell entry mechanisms of SARS-CoV-2

J Shang, Y Wan, C Luo, G Ye, Q Geng… - Proceedings of the …, 2020 - National Acad Sciences
… binding and protease activations of SARS-CoV-2 spike, using SARS-CoV spike as a
comparison. Our results identify important cell entry mechanisms of SARS-CoV-2 that potentially …