… dysregulated immune response and cytokine storm caused extensive lung … cytokines (tumor
necrosis factor [TNF], Interleukin-1β [IL-1β], IL-6, IL-12, and transforming growth factor-β) as …

… discrete stimulus including ligands of tumour necrosis factor receptor (TNFR) superfamily
members such as lymphotoxin-β receptor (LTβR) [40], B-cell activating factor receptor (BAFFR) […

… , which secrete large amounts of cytokines, causing a cytokine storm. Many clinical features
… cytokines, such as interferon (IFN)-γ, tumor necrosis factor (TNF), interleukin (IL)-1, IL-6, and …

… Chloroquine and hydroxychloroquine equally affect tumor necrosis factor-alpha, interleukin
6, and interferon-gamma production by peripheral blood mononuclear cells. J Rheumatol. …

… They also facilitate the upregulation of tumor necrosis factor receptor-associated factor (TRAF)
[Citation8]. The Janus Kinase/Signal Transducers and Activators of Transcription (JAK/…

… Activation of various kinases (IRAKs, TBK1, and IKKs) and tumor necrosis factor receptor-related
factor 6 (TRAF6), according to the different adaptors, eventually lead to activation of the …

… If the inflammatory reaction is very pronounced, an ultimately uncontrolled release of
proinflammatory cytokines leads to cytokine storm with the known … TNF tumor necrosis factor …

… cytokines like interferon (IFN)-γ, tumor necrosis factor (TNF)-α, interleukin (IL)-2, IL-4, … “cytokine
storm” that may have occurred due to an imbalanced immune system. The cytokine storm …

… exchange (TPE) to treat cytokine storm in severe COVID-19. … cytokines from the blood and
can improve cytokine storm 7 . … cytokines were also noted in the early phase: tumor necrosis …

… levels of pro-inflammatory cytokines are produced during the crosstalk between epithelial
cells and immune cells in COVID-19, which has linked the cytokine storm (CS) with the severe …