The cytokine storms of COVID-19, H1N1 influenza, CRS and MAS compared. Can one sized treatment fit all?

G Morris, CC Bortolasci, BK Puri, W Marx, A O'Neil… - Cytokine, 2021 - Elsevier
… This is characterised by increased levels of tumour necrosis factor (TNF)-α, interleukin (IL)-1β,
IL-6, IL-18, IL-10, monocyte chemoattractant protein-1 (MCP-1) and interferon (IFN)-γ-…

Radiotherapy and cytokine storm: risk and mechanism

C Zhang, Z Liang, S Ma, X Liu - Frontiers in Oncology, 2021 - frontiersin.org
… Plasmin inhibition could control the deadly cytokine storm in patients with … cytokines including
tumor necrosis factor-α and Fas-ligand directly. It could also relieve the cytokine storm via …

Cytokine storm: When the immune system goes into overdrive

PP Kale, A Mani, S Gurha, HN Abhishek… - Journal of Cellular …, 2023 - content.iospress.com
… and secondary cytokine storms. Primary cytokine storm: This type of cytokine storm is caused
… such as interleukin-6 (IL-6) or tumor necrosis factor-alpha (TNF-alpha) can be effective in …

[HTML][HTML] Agents to reduce cytokine storm

H Gerlach - F1000Research, 2016 - ncbi.nlm.nih.gov
tumor necrosis factor (TNF) or IL-1, thus causing cardiovascular insufficiency, hypotension,
and decreased end-organ perfusion. The first large randomized controlled trial (RCT) using a …

Targeting cytokine storm as the potential anti-viral therapy: Implications in regulating SARS-CoV-2 pathogenicity

S Maity, A Santra, AV Hebbani, S Pulakuntla… - Gene, 2023 - Elsevier
Cytokine storm in patients with severe symptoms is understood to be characterized by
enhanced serum levels of many cytokines including interleukin-1β, … Tumor necrosis factor

Cytokine storm and neuropathological alterations in patients with neurological manifestations of COVID-19

C Tsagkaris, M Bilal, I Aktar, Y Aboufandi… - Current Alzheimer …, 2022 - ingentaconnect.com
… because it stimulates the production of other pro-inflammatory cytokines like interleukin-6
and tumour necrosis factor-alpha. Despite promising early results, further clinical studies with …

The roles of neutrophils in cytokine storms

L Chan, N Karimi, S Morovati, K Alizadeh, JE Kakish… - Viruses, 2021 - mdpi.com
… )-γ, monocyte chemoattractant protein (MCP)-1, and granulocyte-macrophage colony-stimulating
factor (GM-CSF) [5]. In addition, tumor necrosis factor (TNF), IL-1, IL-2, IL-2-receptor-α, …

Critical determinants of cytokine storm and type I interferon response in COVID-19 pathogenesis

S Ramasamy, S Subbian - Clinical microbiology reviews, 2021 - Am Soc Microbiol
… Severe COVID-19 manifests as acute respiratory distress syndrome (ARDS) with elevated
plasma proinflammatory cytokines, including interleukin 1β (IL-1β), IL-6, tumor necrosis factor

Tackling the cytokine storm in COVID-19, challenges and hopes

SM Abdin, SM Elgendy, SK Alyammahi, DW Alhamad… - Life Sciences, 2020 - Elsevier
… receptors (TLRs), they activate the nuclear factor of кB (NF-ĸB) to generate different cytokines,
among which is tumor necrosis factor (TNF), and interleukins (IL): (IL-1β, IL-6, IL-18) [24]. IL…

Cyclosporine therapy in cytokine storm due to coronavirus disease 2019 (COVID-19)

E Cure, A Kucuk, M Cumhur Cure - Rheumatology international, 2020 - Springer
… several cytokine storm mediators from monocytes, neutrophils, and endothelial cells [13].
Cyclosporin prevents cytokine storm … of the transmembrane protein tumor necrosis factor-alpha. …