A comparative study of structural and conformational properties of WNK kinase isoforms bound to an inhibitor: insights from molecular dynamic simulations

NA Jonniya, MF Sk, P Kar - Journal of Biomolecular Structure and …, 2022 - Taylor & Francis
The with-no-lysine (WNK) kinase causes pseudohypoaldosteronism type II, a genetic form of
hypertension. Due to∼ 80% similarity among four isoforms (WNK1/2/3/4) of the WNK protein …

A comparative study of structural and conformational properties of WNK kinase isoforms bound to an inhibitor: insights from molecular dynamic simulations

NA Jonniya, MF Sk, P Kar - Journal of Biomolecular Structure …, 2022 - ingentaconnect.com
The with-no-lysine (WNK) kinase causes pseudohypoaldosteronism type II, a genetic form of
hypertension. Due to∼ 80% similarity among four isoforms (WNK1/2/3/4) of the WNK protein …

A comparative study of structural and conformational properties of WNK kinase isoforms bound to an inhibitor: insights from molecular dynamic simulations.

NA Jonniya, MF Sk, P Kar - Journal of Biomolecular Structure & …, 2020 - europepmc.org
The with-no-lysine (WNK) kinase causes pseudohypoaldosteronism type II, a genetic form of
hypertension. Due to∼ 80% similarity among four isoforms (WNK1/2/3/4) of the WNK protein …

A comparative study of structural and conformational properties of WNK kinase isoforms bound to an inhibitor: insights from molecular dynamic simulations

NA Jonniya, MF Sk, P Kar - Journal of biomolecular …, 2022 - pubmed.ncbi.nlm.nih.gov
The with-no-lysine (WNK) kinase causes pseudohypoaldosteronism type II, a genetic form of
hypertension. Due to∼ 80% similarity among four isoforms (WNK1/2/3/4) of the WNK protein …