The effect of initial antipsychotic treatment on hippocampal and amygdalar volume in first-episode schizophrenia is influenced by age

M Xia, Y Wang, W Su, Y Tang, T Zhang, H Cui… - Progress in Neuro …, 2023 - Elsevier
Patients with FES showed baseline reductions in amygdala … more serious longitudinal
cortical thinning in the temporal … to be key regions for the age-related biological mechanism of …

Grey matter connectome abnormalities and age-related effects in antipsychotic-naive schizophrenia

B Yang, W Zhang, R Lencer, B Tao, B Tang, J Yang… - …, 2021 - thelancet.com
age-related cortical thinning in prefrontal and temporal regions [ … of first episode drug-naïve
schizophrenia patients and … left thalamus), but exhibited age-related decline or DUP-negative …

Antipsychotic treatment effects and structural MRI brain changes in schizophrenia

R Emsley, S du Plessis, L Phahladira… - Psychological …, 2023 - cambridge.org
… 99 minimally treated patients with first-episode schizophrenia, … In this study, we found
reductions in global cortical thicknessAge-related changes in frontal and temporal lobe volumes …

[PDF][PDF] General and specific cortical thickness-cognition associations in first-episode psychosis

… is observed in psychosis, is associated with cognitive and clinical symptoms and
functioning, and may be statistically obscured by a global reduction in cortical thickness. …

Cortical and subcortical structural morphometric profiles in individuals with nonaffective and affective early illness psychosis

JPY Hua, DH Mathalon - Schizophrenia Bulletin Open, 2022 - academic.oup.com
… for cortical thickness (P < .001), with NAff-P having widespread cortical thinning relative to
… Relative to HC, the NAff-P group showed a reduction in cortical thickness across most ROIs, …

Structural covariance predictors of clinical improvement at 2-year follow-up in first-episode psychosis

C Saiz-Masvidal, F Contreras, C Soriano-Mas… - Progress in Neuro …, 2023 - Elsevier
… included patients with evidence of a first episode with … patients with first-episode psychosis.
Using a cut-off point of 40% symptom reduction between baseline and follow-up, 29 patients

Brain Age Gap in Early Illness Schizophrenia and the Clinical High-Risk Syndrome: Associations With Experiential Negative Symptoms and Conversion to Psychosis

JPY Hua, SV Abram, RL Loewy, B Stuart… - Schizophrenia …, 2024 - academic.oup.com
… Preliminary first-episode/recent onset psychosis MRI studies … cortical thickness metrics, 68
unilateral Desikan-Killiany atlas … to disentangle natural age-related processes from disease-…

A 24-month advanced magnetic resonance imaging study of multiple sclerosis patients treated with alemtuzumab

IM Vavasour, R Tam, DKB Li, C Laule… - Multiple Sclerosis …, 2019 - journals.sagepub.com
… BPF, cortical thickness and CC area all showed decreases in … decreasing MWF and FA,
stable or decreasing NAA … ) and ≥2 MS attacks (first episode or relapse) occurring in the 24 …

Morphological alterations of the corpus callosum in antipsychotic-naive first-episode schizophrenia before and 1-year after treatment

B Tao, Y Xiao, B Yang, J Zeng, W Zhang, N Hu… - Schizophrenia …, 2021 - Elsevier
… in patients with schizophrenia. However, its morphologic characteristics are less well studied
in treatment-naive first-episode schizophrenia patients… a significant reduction of thickness in …

The interaction between first-episode drug-naïve schizophrenia and age based on gray matter volume and its molecular analysis: a multimodal magnetic resonance …

J Chen, Y Wei, K Xue, S Han, C Wang, B Wen… - …, 2023 - Springer
… We emphasized age-related GM abnormalities of ventral stream of visual … reduction in
GMV in frontal, parietal, temporal, occipital cortices and subcortical structures of FES patients, …